摘要
长期以来，血管紧张素－（１—７）（Ａｕｇ－（１—７］一直被认为是血管紧张素！的无生物活性代谢产物。近年的研究证明Ａｎｇ－（１—７）在神经系统和心血管功能调节中起有作用，是血管紧张素系统中一种新的重要激素。本文根据最近的研究主要讨论了四个问题：（１）Ａｎｇ－（１—７）的存在部位；（２）Ａｎｇ－（１—７）的形成；（３）Ａｕｇ－（１—７）的生理学效应；（４）Ａｎｇ－（１—７）的抗高血压作用，最后对这一激素的目前认识作了小结。
Angiotensin-(1-7) was considered as an inactive metabolite of angiotensin Ⅱ for a long time. However, new studies have shown that angiotensin-(1-7) is a new hormone of the angiotensin system which plays an important role in the modulation of cell-to-cell interactions in cardiovascular and neural function. On the basis of results obtained from the re- cent research, four basic aspects are discussed, including: (1) where is angiotensin-(1-7) present? (2) process of angiotensin-(1-7 ) formation: (3) physiological effects of an- giotensin- (1-7) 1 and (4) Antihypertensive actions of angiotensin-(1-7 ). Finally, the current knowledge on the substance is summarized.
出处
《动物学报》
SCIE
CAS
CSCD
1996年第4期394-400,共7页
ACTA ZOOLOGICA SINICA
基金
香港理工大学研究基金(A/C 351/055
350/539
350/314)资助。
关键词
血管紧张素
肾素
血管紧张素
系统
Angiotensin-(1-7), Antihypertensive actions, Location and formation, Physiological effects.
