摘要
目的探讨尿毒症并发上消化道出血的危险因素与防治。方法将162例尿毒症患者中并发上消化道出血者60例分为出血组,余无上消化道出血者102例为未出血组。两组间分别从年龄、凝血酶原时间(PT)、血小板(PLT)、血清胃泌素(ser-um gastrin,SG)、肾功能(BUN、Cr)、血钙(Ca2+)、血红蛋白(Hb)等指标进行观察比较。结果出血组在年龄、凝血酶原时间、胃泌素、血红蛋白、肾功能改变及血钙变化等方面与未出血组比较差异有统计学意义(P<0.05),两组间血小板数量比较差异无统计学意义(P>0.05)。结论高龄、凝血功能障碍、胃泌素水平增高、贫血、低钙、透析不充分及透析时肝素使用是尿毒症并发上消化道出血的危险因素,临床上应根据其变化及早防治。
Objective To investigate the risk factors and prevention of upper digestive tract bleeding complicated by uremia. Methods Taking 60 patients with upper digestive tract bleeding complicated by uremia in 162 uremia patients as the bleeding group, other 102 patients without upper digestive tract bleeding as the unbleeding group. For two groups, making observations and comparisons respectively from age, prothrombin time （PT）, platelet（Plt）, serum gast rin（SG）, renal function （BUN, Cr）, calcemia （Ca^2＋ ）, hemoglobin （Hb） ,etc. Results The bleeding group had marked differences on age, prothrombin time, gastrin, hemoglobin, renal dysfunction etc compared with the unbleeding group（P〈0.05）. There was not marked difference for platelet numbers of two group（P〈0.05）. Conclusion Old age, clotting dusfanction, gastrin level increase, anemia, low calcemia, not plenty dialysis and using heparin when dialyzing,are the risk factors for upper digestive track bleeding complicated by uremia, clinically it should be prevented early in time according to changes of these factors.
出处
《重庆医学》
CAS
CSCD
2006年第15期1390-1391,共2页
Chongqing medicine
关键词
尿毒症
上消化道出血
危险因素
uremia
upper digestive track bleeding
risk factor
