摘要
从通关藤（Ｍａｒｓｄｅｎｉａｔｅｎａｃｉｓｓｉｍａ（Ｒｏｘｂ．）ＷｉｇｈｔｅｔＡｒｎ）中分得多个Ｃ_（２１），甾体甙类化合物。通过ＦＡＢＭＳ、￣１ＨＮＭＲ、￣（１３）ＣＮＭＲ、￣１Ｈ－￣１ＨＣＯＳＹ、ＬＳＰＤ、ＴＯＣＳＹ、ＨＭＱＣ、ＨＭＢＣ等光谱分析，确定了其中３个新化合物的化学结构。
Three new C_(21)-steroidal glycosides(tenacissimoside A, B, C) wereisolated from the Chinese crude drug 'Tong-guan-teng': the stems of Marsdeniatenacissima (Roxb.) Wight et Arn(Asclepiadaceae). The chemical structures of tenacissimoside A, B, C were deduced by means of chemical and spectral evidence as 11α-O-tigloyl-12β-O-acetyl tenacigenin B 3-O-[3-O-methyl6-deoxy-β-D-allopyranosyl- (1→4) -β-D-oleandropyranoside] (Ⅰ); 11α-O-benzoy-12β-O-acetyl tenacigenin B 3-O- [3-O-methyl-6-deoxy-β-D-allopyranosyl-(1→4)-β-D-oleandropyranoside](Ⅱ) and 11α-O-(2-methyl butanoyl)-12-β-O-acetyl tenacigenin B3-O-[3-methyl-6-deoxy-β-D-allopyranosyl-(1→4)-β-D-oleandropyranoside] (Ⅲ).
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
1996年第9期391-395,共5页
Chinese Journal of Pharmaceuticals
关键词
通关藤
通关藤新甙
C21
甾体甙
结构分析
Marsdenia tenacissima, Pregnane glycosides, tenacissimosidesA～C.
