摘要
目的观察住院精神病患者口咽部革兰阴性(G-)杆菌定植的改变,为控制呼吸道感染提供科学依据。方法采集92例住院精神病患者不同时期的咽拭子标本进行细菌培养鉴定,并分析G-杆菌定植的相关医疗因素。结果患者入院后第1天和第5天口咽部G-杆菌定植率分别为9.8%、22.8%(以克雷伯杆菌、大肠杆菌和绿脓杆菌为主),住院第5天患者口咽部G-杆菌定植呈明显上升趋势(P<0.05),这一改变与患者精神症状、药物不良反应、约束护理、生活自理能力差、睡眠差、进食少有关,与年龄、住院频率无关。结论需加强精神病患者急性期的病情观察和治疗,以减少G-杆菌定植,有效预防呼吸道感染的发生。
Objective To observe the changes of oropharyngeal swab gram negtive（G ） bacilli colonized in mental inpatients, offering scientific theory for controlling nosocomial infection of respiratory tract. Methods Ninety-two inpatients＇ pharyngeal swab samples in various periods were colleated, germiculture identification done, related medical treatment factors of G bacilli colonized analyzed. Results One and 5 days after admission, colonization isolation rate of the G bacilli in oral swab was 9.8% and 22.8 % respectively （the majority of Klebsiella and Escherichia coli ）, implicating oral swab G bacilli colonized in mental patients was increased during the primary period （P〈0.05）. This change was related with psychosis symptoms, the side effect of antipsyehotie drugs, binding nursing, self-life ability difficulty, insomnia, less diet, but not related with ages and hospitalization times. Conclusion To intensify the observation of the disease and treatment in acute period is the key to decrease G bacilli colonized and effectively prevent nosocomial infection of respiratory tract.
基金
2004年度深圳市科技局立项课题(200405052)
关键词
精神病
口咽部
革兰阴性杆菌定植
护理
mental disorder
oropharynx
gram negative bacilli colonization
nursing care
