期刊文献+

基质金属蛋白酶在圆锥角膜发病机制中的作用 被引量:4

Role of matrix metalloproteinases in the pathogenesis of keratoconus
下载PDF
导出
摘要 圆锥角膜是一种先天性发育异常,是一种以角膜扩张为特征,致角膜中央部向前凸出、变薄呈圆锥并产生高度不规则散光的角膜病变。其病因不明,有研究表明基质金属蛋白酶可能参与了它的发病过程,现将这方面的研究近况作一综述。 Keratoconus is an uncommon autosomal recessive inheritance, characteristic of corneal ectasia, which results in the corneal central anterior bulging, conus formation and high irregular astigmatism. The etiopathogenisis is not clear and some research indicate that matrix metaUoproteinascs probably involved in the pathogenesis of keratoconus. Now we make a review of recent developments.
出处 《眼科新进展》 CAS 2006年第8期635-637,共3页 Recent Advances in Ophthalmology
关键词 圆锥角膜 基质金属蛋白酶 胶原 keratoconus matrix metallopro-teinases collagen
  • 相关文献

参考文献43

  • 1Bauer EA,Eisen AZ,Jeffrey JJ.Immunologic relationships of a purified human skin collagenase to other human and animal collagenases[J].Biochem Biophys Acta 1970 ;206:152-160. 被引量:1
  • 2Visse R,Nagase H.Matrix metalloproteinases and tissue inhibitors of metalloproteinases:structure,function,and biochemistry[J].Circ Res 2003;92:827-839. 被引量:1
  • 3Nagase H.Activation mechanisms of matrix metalloproteinases[J].Biol Chem 1997; 378:151-160. 被引量:1
  • 4Wang Z,Juttermann R,Soloway PD.TIMP-2 is required for efficient activation of proMMP-2 in vivo[J].J Biol Chem 2000; 275:26411-26415. 被引量:1
  • 5Strongin AY,Collier I,Bannikov G,Marmer BL,Grant GA,Goldberg GI.Mechanism of cell surface activation of 72-kDa type Ⅳ collagenase:isolation of the activated form of the membrane metalloprotease[J].J Biol Chem 1995; 270:5331-5338. 被引量:1
  • 6Butler GS,Will H,Atkinson SJ,Murphy G.Membranetype-2 matrix metalloproteinase can initiate the processing of progelatinase A and is regulated by the tissue inhibitors of metalloproteinases[J].Eur J Biochem 1997;244:653-657. 被引量:1
  • 7Takino T,Sato H,Shinagawa A,Seiki M.Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library:MT-MMPs form a unique membrane-type subclass in the MMP family[J].J Biol Chem 1995; 270:23013-23020. 被引量:1
  • 8Llano E,Pendas AM,Freije JP,Nakano A,Knauper V,Murphy G,et al.Identification and characterization of human MT5-MMP,a new membrane-bound activator of progelatinase A overexpressed in brain tmors[J].Cancer Res 1999;59:2570-2576. 被引量:1
  • 9Pei D.Identification and characterization of the fifth membrane-type matrix metalloproteinase MT5-MMP[J].J Biol Chem 1999;274:8925-8932. 被引量:1
  • 10Velasco G,Cal S,Merlos-Suarez A,Ferrando AA,Alvarez S,Nakano A,et al.Human MT6-matrix metalloproteinase:identification,progelatinase A activation,and expression in brain tumors[J].Cancer Res 2000; 60:877-882. 被引量:1

二级参考文献27

  • 1[1]Fratze P, Daxer A. Structural transformation of collagen fibrils in corneal stroma during drying:An scattering study[J]. Biophys J 1993;64∶1210-1214. 被引量:1
  • 2[2]David A, Foidart JM, John R. Detection of specific collagen types and keratoconus corneas[J]. Invest Ophthalmol Vis Sci 1981;20∶738-750. 被引量:1
  • 3[3]Tsuchiya S, Tanaka M, Konomi H. Distribution of specific collagen types and fibronectin in normal and keratoconus corneas[J]. Am J Ophthalmol 1986;30∶14-31. 被引量:1
  • 4[4]Tsubota K, Mashima Y, Murata H. Corneal epithelium in keratoconus[J]. Cornea 1995;14∶77-83. 被引量:1
  • 5[5]Birk DE, Fitch JM, Babiarz JP. Collagen type I and type V are present in the same fibril in the avian corneal stroma[J]. J Cell Biol 1988;106(3)∶999-1008. 被引量:1
  • 6[6]Peters DP, Harrison DA, Brandt CR. Heterogeneity of type I collagen expression in human corneal keratoconus fibroblasts[J]. Ophthalmic Res 1993;25(5)∶273-279. 被引量:1
  • 7[7]Trelstad RL, Coulombre AJ. Morphogenesis of the collagenous stroma in the chick cornea[J]. J Cell Biol 1971;50∶840. 被引量:1
  • 8Jefferies LW,Alexander RA.Connective tissue fibre production in keratoconus.BrJ Biomed Sci,1995,52∶14 被引量:1
  • 9Marshall GE,Konstas AG,Lee WR.Immunogold fine structural localization ofextracellular matrix components in aged human cornea.Ⅱ.Collagen types Ⅴ and Ⅵ.GraefesArch Clin Exp Ophthalmol,1991,229∶164 被引量:1
  • 10Sawaguchi S,Yue BYJT,Sugar J,et al.Lysosomal enzyme abnormalities inKeratoconus.Arch Ophthalmol,1989,107∶1507 被引量:1

共引文献9

同被引文献50

引证文献4

二级引证文献13

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部