摘要
目的:观察鸡尾酒疗法对缺血性脑卒中患者运动功能的影响。方法:选择2004-01/2005-03在昆明医学院第一附属医院神经内科住院的颈内动脉系统急性缺血性卒中患者80例。①按住院时间顺序每3例分在1组的方法随机分为对照组39例,治疗组41例。对照组给予常规治疗(对症、抗血小板聚集、脱水降颅压、神经营养剂、防治并发症等治疗),治疗组在常规治疗基础上加鸡尾酒疗法(三七总皂苷、康复训练、电针及高压氧治疗)。②分别于入组时及治疗3周后进行功能评估。日常生活活动能力评分,采用修订Barthel指数评分,评分越高,依赖程度越低;肢体功能缺失评分,采用欧洲卒中量表评分,总分100分,得分越高,说明神经功能受损越少。结果:对照组退出治疗2例,进入结果分析78例。①欧洲脑卒中量表评分结果:对照组和治疗组治疗后评分均明显高于治疗前(对照组:56.58±16.13,42.53±12.02,P=0.000;治疗组:70.72±18.07,44.17±14.63,P=0.000);治疗组治疗后评分显著高于对照组(P=0.000)。②Barthel指数评分结果:对照组和治疗组治疗后评分均明显高于治疗前(对照组:58.37±14.66,48.37±13.37,P=0.000;治疗组:75.34±15.36,51.66±11.56,P=0.000);治疗组治疗后评分显著高于对照组(P=0.000)。结论:鸡尾酒疗法可以促进缺血性卒中患者运动功能的改善。
AIM： To study the effects of cocktail treatment on motor function of patients with ischemic stroke.
METHODS： Eighty inpatients with acute isehemic stroke of internal carotid system （ICS） were selected from the Department of Neurology, First Affiliated Hospital of Kunming Medical College between January 2004 to March 2005. ①Subjects were randomly divided into control group （n=39） and treatment group （n=41） accordingto the enrolled sequence with 3 cases in one group. Patients in the control group were given of conventional therapy （expectant treatment, anti-platelet aggregation, decompression by dehydration, neurotrophy, prevention and cure of complications, etc.）. Based on conventional therapy, patients in treatment group received cocktail treatment （notoginseng saponin, rehabilitation training, electroacupuncture and hyperbaric oxygen treatment）.②Functional assessment was conducted respectively at enrollment and 3 weeks after treatment. Active ability in daily life was assessed by using revised Barthel index （BI）. The higher the score was, the less the dependence was. Loss of function in limbs were scored by European Stroke Scale （ESS） with the total score of 100 points. The higher the score was, the less the neurofunctional damage was.
RESULTS： Two patients in the control group withdrew from the therapy, and a total of 78 cases were involved in the analysis of results. ①Scores of ESS： Those in both groups after treatment were obviously higher than those before treatment （control group： 56：58±16.13,42.53±12.02,P=0.000; treatment group： 70.72±18.07,44.17±14.63,P=0.000）. While score of treatment group after treatment was significantly higher than that in the control group （P=0.000）. ②Seores of BI： Those in both groups were remarkably higher than those before treatment （control group： 58.37±14.66, 48.37 ± 13.37, P=0.000 ; treatment group：75.34 ± 15,36,51.66±11.56, P=0,000）. Score in the treatment group after treatment was markedly higher
出处
《中国临床康复》
CSCD
北大核心
2006年第32期6-8,共3页
Chinese Journal of Clinical Rehabilitation
