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美常安联合柳氮磺吡啶治疗溃疡性结肠炎22例 被引量:19

Therapeutic effect of Medilac-S combined with sulfasalazine in treatment of ulcerative colitis:an analysis of 22 cases
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摘要 目的:评价联合美常安治疗溃疡性结肠炎 (UC)的疗效.方法:轻、中度活动期UC患者46例,随机分为美常安加柳氮磺吡啶(SASP)治疗组(n=22) 和SASP对照组(n=24),评价治疗前后总的疗效、主要症状的变化.结果:治疗组总有效率为91.66%,明显高于对照组(总有效率为68.18%);腹痛、腹泻、黏液血便、里急后重主要症状变化的比较二组间有统计学意义(P<0.05).结论:联合美常安治疗溃疡性结肠炎比单用 SASP疗效好. AIM: To evaluate the therapeutic effect of Medilac-S combined with sulfasalazine (SASP) in the treatment of ulcerative colitis (UC). METHODS: Forty-six patients with mild or moderate UC (active phase) were divided into group A (n = 22) and B (n = 24). The patients in group A were treated with Medilac-S and SASP, while those in group B, serving as the controls, were treated with SASP. The total efficacy rate and the changes of main symptoms were statistically analyzed. RESULTS: The overall efficacy of group A was 91.66%, which was higher than that of the controis (68.18%, P 〈 0.05). There was significant difference before and after treatment, as well as between the two groups (P 〈 0.05) in the changes of abdominal pain, diarrhea, mucus bloody stool and tenesmus (P 〈 0.05). CONCLUSION: Combination of Medilac-S and SASP is superior to SASP alone in the treatment of UC.
出处 《世界华人消化杂志》 CAS 北大核心 2006年第17期1742-1744,共3页 World Chinese Journal of Digestology
关键词 溃疡性结肠炎 美常安 治疗 Ulcerative Colitis Medilac-S Treatment
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  • 1欧阳钦,万学红,温忠慧,胡仁伟.全国炎症性肠病学术会议纪要[J].中华消化杂志,2001,21(4):235-236. 被引量:27
  • 2张达荣主编..消化系疾病与微生态[M].上海:上海科学技术出版社,2001:497.
  • 3Guarner C,Runyon BA,Young S,Heck M,Sheikh MY.Intestinal bacterial overgrowth and bacterial translocation in cirrhotic rats with ascites.J Hepatol1997; 26:1372-1378 被引量:1

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