摘要
目的观察联合希罗达与紫杉醇治疗晚期胃癌的疗效与毒副反应。方法对68例晚期胃癌患者进行回顾性统计分析。结果CR6%,PR47%,NC22%,PD25%。症状缓解率81%。一年总生存率72%。平均缓解时间5.5月。化疗副反应包括恶心呕吐(86%),手足综合征(45%);Ⅰ、Ⅱ度骨髓抑制(55%)及Ⅲ、Ⅳ度骨髓抑制(12%);无化疗相关死亡。结论希罗达加紫杉醇方案对晚期胃癌疗效较好,毒副作用较轻。
Objective To observe the effect and side-effect of combining capecitabine with taxol to treat advanced gastric cancer. Methods Review and analyse clinical data of 68 patients with advanced gastric cancer. Results Among the patients studied, CR, PR, NC, and PD was 6%, 47%, 22%, and 25%, respectively; one year survival rate was 72%, DST 5.5 months, symptom remission rate 81%. Side-effects included mild nausea and vomiting （86%）, palmar-plantar syndrome（45%）,Ⅰ ,Ⅱ degree bone marrow inhibition（55%）, Ⅲ,Ⅳ degree 12%, and no chemotherapy-related death occurred. Conclusion Combination of capecitabine and taxol is effective for advanced gastric cancer, and the side effect is mild.
出处
《现代消化及介入诊疗》
2006年第2期66-67,共2页
Modern Interventional Diagnosis and Treatment in Gastroenterology
关键词
晚期胃癌
紫杉醇
希罗达
Advanced gastric cancer
Capecitabine
Taxol
