摘要
目的：探讨16层螺旋（汀低剂量扫描在肺普查中的应用价值。方法：对1206名体检者行16层螺旋CT低剂量肺扫描，扫描参数为管电压120KV，管电流25mA，层厚7．5mm，螺距1．35，床速27．5nma／圈。对15例小结节提高管电流至180mA重复扫描，进行对比。发现疑似或肯定的小结节就选择1．25mm层厚和1．25mm的间隔重建．再应用高级肺结节分析软件定量分析小结节的容积、密度。结果：共检出各类肺部疾病265例，阳性率为21．97％。检出非钙化性肺小结节97例，检出率为8．04％。发现的小结节直径为3—30mm。在对15例两种剂量扫描的小结节测量体积时，尽管低剂量扫描的体积要大于正常剂量扫描的体积，但是，其差异无显著性（t=1．747，0．2〉P〉0．1）。有12例3—4mm钙化性小结节未重建前测得的的最高点密度CT值为-571—61HU，重建后为399—1880HU，有明显差异（t=12．95，P〈0．001）。结论：低剂量螺旋CT以发现3mm以上的小结节为主要目的。其射线剂量低，明显减少了对人群的辐射危害．完全可以应用于健康人群普查以利于早期肺癌的筛选和诊断。
Objective：To assess the value of clinical application in lung general investigation with 16-slice helical CT low-dose scan. Methods： Thoracic 16-slice helical CT low-dose scanning was separately performed in each of 1206 asymptomatic volunteers with the scan parameters as follows： 120kV, 25mA, thickness 7.Smm, pitch 1.35 and table speed 27.Store/rotation. 15 cases with small nodules were examined repeatedly rising to standard-dose of 180 mA and compared the results with the former. The cases with definite nodule or questionable nodule underwent 1.25mm reconstruction slice and 1.25mm reconstruction interval. The volume and the density of small nodules were analyzed by the Advance Lung Analysis.Results：Different diseases in lung were detected in 265 cases totally and the positive rate was 21.97%. 97 cases with non-calcification pulmonary nodules from 3 - 30mm were examined and the positive rate was 8.04%. The volume of the nodules were successfully measured with two kinds of doses in 15 cases and the figures with low-dose scan were larger than those with standard - dose scan but without statistically significant differences （ t = 1. 747, 0.2 〉 P 〉 0.1 ）. Before 1.25mm reconstruction interval the highest density CT values - 571 ～ 61HU were measured from 3 ～ 4mm calcification pulmonary nodules in 12 patients and the values became 399 ～ 1880HU after 1.25mm reconstruction interval. There was statistically significant difference between the two methods （ t = 12.95, P 〈 0.001）. Conclusion：Low-dose helical CT is expected to detect the lung nodules larger than 3mm. Due to the low dose, the negative influences of radio can be reduced significantly. It may be appropriate on the healthful examina- tion for the lung cancer detection on early stage and make the diagnosis.
出处
《医学影像学杂志》
2006年第7期697-700,共4页
Journal of Medical Imaging
