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早期类风湿关节炎指标的评价 被引量:1

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摘要 目的:了解类风湿关节炎(RA)患者血清中抗环瓜氨酸肽抗体(抗ccp)、抗角蛋白抗体(抗AKA)、抗RA33抗体对RA诊断的灵敏度、特异性及其在风湿性疾病中的临床价值并进行评价。方法:采用ELISA法检测抗ccp、抗RA33抗体,间接免疫荧光法检测抗AKA抗体,共检测RA63例,非RA风湿病104例和50例正常健康人。结果:63例RA患者中抗cc、抗AKA、抗RA33抗体的灵敏度分别为59.2%、28.0%、38.0%;特异性分别为95.0%、94.4%、96.0%;三者灵敏度差异有显著性,特异性无差异显著性。结论:抗ccp、抗AKA、抗RA33抗体对RA早期诊断有良好的灵敏度和特异性,联合检测特异性显著提高。
出处 《实用医学杂志》 CAS 2006年第15期1820-1821,共2页 The Journal of Practical Medicine
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