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药物洗脱支架应用现状和展望 被引量:4

The Status and Prospect of Drug-Eluting Stents(DES) in Percutaneous Coronary Intervention(PCI)
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摘要 支架内再狭窄一直是多年来制约冠心病介入治疗远期疗效的瓶颈,人们形象的称之为冠脉介入治疗的阿喀琉斯之踵(Achilles’heel)。但随着近年来药物洗脱支架(Drugelutingstent,DES)的迅猛发展,有望成为支架内再狭窄这一顽症的理想解决方案之一,同时随着相关临床试验的结果公布,DES在冠心病介入治疗中的应用领域也不断扩展,而且DES作为一种新兴的医疗器械仍在作进一步的研发,各种新型药物支架的诞生将丰富冠脉介入治疗的手段,为广大冠心病患者造福。 Percutaneous transluminal coronary angioplasty(PTCA) and stents are presently potential strategies against coronary artery diseases.However,the long-term outcome of these techniques is limited by in-stent restenosis(ISR).With the recent advent of drug-cluting stents (DES),we discover a new promising weapon to overcome the "Achilles' heel "of interventional cardiology.Recently,more and more clinical data on DES from trials are encouraging us to use it against more challenging coronary lesions such as chronic total occlusions,comlpex lesions and multivessel lesions.With the research and development of better devices,the treatment of coroaary artery disease will improve.w
作者 沈雳 葛均波
出处 《中国医疗器械信息》 2006年第7期8-12,共5页 China Medical Device Information
关键词 支架 冠心病 再狭窄 药物 介入冶疗 Stent,Coronary Disease,Restenosis,Drug,Percutaneous Coronary Intervention(PCI)
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