摘要
用４种抗丙型肝炎病毒蛋白的单克隆抗体，免疫酶染色法直接检测肝细胞癌的病理组织中丙肝病毒蛋白。结果８／５２例（１５．４％）—至数种抗体阳性。阳性反应物主要定位于肝和癌细胞的胞浆中。值得注意的是本组几乎全部病例为乙肝、丙肝两种病毒混合感染。表明广西丙型肝炎混合感染的比例高，乙型肝炎病毒（ＨＢＶ）加上黄曲霉毒素（ＡＦＢ１）或丙型肝炎病毒（ＨＣＶ）可能是广西肝细胞癌（ＨＣＣ）高发的原因。
Four Kinds of anti-HCV mono-clone antibodies were used for immunohistochemical stain to direct detection of viral protein in tissues of HCC.The result was positive in 8/52 cases (15.4%) which were reactive at least for one mono clone antibodies.The material of positive reaction was located at the cytoplasma of cancer cell.It was interested that this series almost all the cases were HBV and HCV mixed infection. Indicating that HBV and HCV mixed infections are high in Guangxi;HBV,AFB1 and HCV may be the cause of high HCC prevanlence in Guangxi.
出处
《广西科学》
CAS
1996年第4期38-40,共3页
Guangxi Sciences
关键词
丙型肝炎病毒
肝细胞癌
混合感染
广西
感染
hepatitis C virus (HCV),hepatocellular carcinoma (HCC),mixed infection
