摘要
目的：探讨门静脉金属内支架结合经动脉化疗栓塞术（TACE）治疗肝癌合并门静脉癌栓的临床效果。方法：11例肝癌门静脉癌栓患者采用肝穿刺途径置入门静脉金属内支架，同时（或1周后）行TACE。记录手术成功、狭窄开通、并发症和手术死亡发生情况，随访支架通畅期和患者生存期。结果：门静脉通路穿刺成功率11／11；门脉支架置入成功率10／11；发生肝性脑病及肝功能衰竭1例。支架中位通畅期5．7个月（1～18个月）；治疗后3个月、6个月及1年患者生存率分别为5／11、4／11、2／11。结论：对巨块型肝癌合并门静脉癌栓、但无远处广泛转移的患者，采用支架开通门脉主干及远端为非肿瘤所在肝叶的门脉，结合TACE治疗，可取得较好的疗效。
Objeetive：To discuss the clinical outcomes of portal vein stenting combined with transeatheter hepatic arterial ehemoembolization （TACE） in treating portal vein tumor thrombus in the patients with primary hepatic carcinoma （PHC）. Methods： Eleven PHC patients with tumor thrombus in the main branch or trunk of the portal vein were treated with stenting and TACE simultaneously （or TACE were performed 1 week later）. The successful rate of the procedure, the pateney of the obstruction, the complications, the mortality and the survival periods were all recorded. Results： Portal vein puncture was sueeessfully performed in all 11 eases and successful stenting was achieved in 10 eases. Hepatic eneephalopathy combined with hepatic failure was noticed in 1 patient. The median pateney period after stenting was 5.7 （1-18） months. The survival rates of patients at 3, 6 and 12 months after treatment were 5/ 11,4/ 11 and 2/ 11, respectively. Conelusion： Metallic stent implantation combined with TACE has satisfactory outcome in treating tumor thrombus in the main branch and trunk of the portal vein in PHC patients without distant metastases.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
2006年第7期771-773,共3页
Academic Journal of Second Military Medical University
关键词
肝肿瘤
门静脉癌栓
金属内支架
门静脉
经动脉化疗栓塞术
liver neoplasms
portal cancerous thrombus
metallic stent
portal vein
transeatheter hepatic arterial ehemoembdization
