摘要
目的观察普伐他汀(普拉固)对不稳定心绞痛患者C反应蛋白的影响。方法将56例不稳定心绞痛患者随机分为两组,对照组给予常规治疗,治疗组在常规治疗的基础上加普伐他汀每日10mg,晚餐后服用,疗程共4周。治疗前后检查C反应蛋白水平和血脂水平。结果治疗后治疗组C反应蛋白(CRP)水平明显降低,与对照组相比差异显著(P<0.01)。而血脂水平无明显变化。结论普伐他汀可以显著降低CRP水平,具有抗炎作用,这种作用独立于降脂作用。
Objective To observe the influence of pravastatin to the CRP in patients with Unstable angina Pectoriso Methods 56 cases with unstable angina pectoris were randomly divided into two groups, contrast group and experimental group. The contrast group had a normal treatment. Besides a normal treatment,the experimental group took 10mg CRP after supper per day. The course lasted for 4 weeds. Levels of CRP and blood fat were checked before and after the treatment. Results In light of significant differences compared with the contrast group, the level of CRP were apparently reduced after the therapy, Yet the level of blood fat had no notable changes. Conclusions Pravastatin can reduce the levels of CRP evidently, and has the effect of anti - inflammation,Which is independent of the function of blood fat reduction.
出处
《医学研究杂志》
2006年第7期50-51,共2页
Journal of Medical Research
