摘要
目的:论述慢性心功能不全(CHF)药物治疗的国内外研究进展。方法:复习近年来国内外有关CHF药物治疗的试验,并结合临床经验进行归纳与分析。结果:对心衰发生与发展机制的认识经历了心-肾机制、心脏-周围循环机制及神经-体液机制3个阶段。CHF的药物治疗主要有血管紧张素转换酶抑制剂(ACEl)、β-受体阻滞剂、利尿剂、洋地黄制剂及非洋地黄类正性肌力药、血管紧张素受体拮抗剂(ARB)和醛固酮拮抗剂。结论:CHF的药物治疗近年来已取得显著进步,降低了CHF患者的病死率和住院率。
Objective： Having a investigation into the CHF medical treatments research condition at home and abroad. Methods： Conducting a survey of the related experiments of the CHF medical treatments at home and abroad combined with the clinical experience treats. Resuits： Of the causes and underlying reasons of the disease , the scientific studies have past three stages ： the Heart - kidney mechanism , the Heart- Periphery circulatory mechanism , and the Nerve - Body fluid mechanism. Medications used to treat CHF mainly include the following ： Angiotensin - converting enzyme inhibitors （ACEI）, Beta - blokers, Diuresis, Digitalis preparation, Non - Digitalis myo - strength medicines, Angiotensin Ⅱ receptor blocker（ARB）, Aldosterone oppresses the anti- medicinal preparation blockers. Conclusions： Substantial achievements have been made in the CHF medical treatments research with a lower percentage of patients becoming dead or being hospitalized.
出处
《中国民康医学》
2006年第14期542-544,546,共4页
Medical Journal of Chinese People’s Health
