摘要
目的 观察高血压病患者动态脉压（PP）与血、尿β2-微球蛋白（β2-MG）的关系，并评价动态PP对反映早期肾损伤的价值。方法 用动态血压监测仪测量223例高血压病患者的动态PP，按动态PP水平分为四组：A组PP≤40mmHg（1mmHg=0．133kPa，54例）、B组PP41～60mmHg（73例）、C组PP61～80mmHg（67例）和D组PP〉80mmHg（29例）。采用免疫比浊法测定研究对象的血、尿β2-MG，并分析动态PP与血、尿β2-MG的关系。结果 随着动态收缩压（SBP）、动态PP水平的增大，血、尿β2-MG浓度明显增加，呈正相关。结论 动态PP与血、尿β2-MG密切相关，动态PP对高血压病早期肾损伤有重要的预测价值。
Objective To observe the relation between the pulse pressure（PP） and β2 -microglobulin （MG） in the hypertension patients, then discuss the value of the patients who suffer from the nephrotic in the prior period. Methods The PP was monitored by ambulatory blood pressure monitoring. All the cases were divided into 4 groups according to the PP：A group（ PP ≤40 mm Hg, 1 mm Hg = 0. 133 kPa） ; B group （ PP 41 - 60 mm Hg ） ; C group （ PP 61 - 80 mm Hg） ; D group （ PP 〉 80 mm Hg ）. The 132 - MG was determined with immunonephelometry. Result The systolic blood pressure （SBP）and PP had a positive effect to the 132 - MG. Conclusion The research indicats that PP is related with 132 - MG. The PP has an important value to the prior hurt of kidney
出处
《中国医师进修杂志（内科版）》
2006年第7期28-29,共2页
Chinese Journal of Postgraduates of Medicine
关键词
高血压病
脉压
Β2-微球蛋白
Hypertension
Pulse pressure
β2 - microglohulin
