摘要
目的:探索逍遥散对肝郁证大鼠中枢神经递质的作用。方法:利用中医证候模型,研究逍遥散对脑内神经递质的作用。结果:肝郁证模型组大鼠脑内NE与DA水平与对照组比较下降明显(P<0.05);肝郁证模型加逍遥散组大鼠脑内NE与DA水平与对照组比较无显著性(P>0.05);结论:肝郁证大鼠脑内NE与DA水平明显降低,逍遥散舒肝解郁,有增加肝郁证大鼠脑内NE、DA神经递质的作用。
Objective：To explore the action of Ease Powder（xiaoyaosan） ,a recipe to treat stasnation of liver- qi and deficiency of blood and spleen, on the central neurotransmitters of rats contracted the stagnation of liver - qi. Method： Applying the symptomatic model of Traditional Chinese Medicine to study the effect of Ease Powder（xiaoyaosan） on the neurotransmitters in the rat＇s brain. Results： Compared with the controlled group, the NE and DA decrease greatly in the brains of rats suffered from the stagnation of livex - qi （ P 〈 0.05 ） ; when the rats having stagnation liver - qi are given Ease Powder（ xiaoyaosan ） , the NE and DA in the brain of rats haven t any obvious change（ P 〈 0.05 ）. Conclusion：When suffered from stagnation of liver- qi, the rats have a considerable reduction of the NE and DA in the brain. Ease Powder（xiaoyaosan） is used to disperse the stagnated livex - qi ,having the function of increasing the neurotransmitter of NE and DA in the rats brains.
出处
《中医药学刊》
2006年第7期1331-1332,共2页
Study Journal of Traditional Chinese Medicine
关键词
肝郁
去甲肾上腺素
多巴胺
逍遥散
大鼠
实验研究
noradrenaline （NE）
dopamine（ DA ）
the stagnation of liver - qi
ease powder（ xiaoyaosan ）
