摘要
目的分析细菌性肝脓肿患者的临床表现、病原学分布及其耐药性。方法回顾性分析267例细菌性肝脓肿患者的临床表现、病原学分布和耐药性。结果267例细菌性肝脓肿患者的主要临床表现为发热(83.89%)、畏寒或寒战(59.18%)、右上腹痛(58.05%)。外周血液白细胞增多占58.80%,门冬氨酸氨基转移酶升高占60.04%,碱性磷酸酶升高占35.96%。所获116株细菌中肺炎克雷伯菌、大肠埃希菌和金黄色葡萄球菌分别占31.03%、27.59%和8.62%。阿米卡星、头孢菌素类和泰能对革兰阴性菌敏感性较好,喹诺酮类和万古霉素对革兰阳性菌敏感性较好。结论肺炎克雷伯菌、大肠埃希菌、金黄色葡萄球菌为细菌性肝脓肿的优势菌,对当前常用抗生素敏感性较好。
Objective TO analyze clinical feature, distribution of bacterial pathogen and antibiotic resistance of bacterial liver abscess. Methods The clinical feature, distribution of bacterial pathogen and antibiotic resistance of 267 patients with bacterial liver abscess admitted in our hospital from June 2000 to June 2005 were retrospectively reviewed. Result The major clinical manifestations were fever （83.89%） ,chill（ 59. 18% ） , abdominal pain in the right upper quadrant （58.05%）. Leukocytosis was observed in 58.80%, increased of transaminase in 60. 04%, and increased of AKP in 35.96%. Among 116 strains. , E. coli, KlebsieUa pneumoniae, S. aureus were the most common （31.03% ,27.59% ,8.62% respectively）. The resistant rates of Gram negative bacteria to amikacin,cephalosporins or imipenem were low and the resistant rates of Gram positive bacteria to quinolones and vancomycin were also low. Conclusions E. coli, KlebsieUa pneumoniae, S. aureus were the most common in patients with bacterial liver abscess, the resistant rates of them to the antibiotics commonly used were low.
出处
《临床内科杂志》
CAS
2006年第7期464-466,共3页
Journal of Clinical Internal Medicine
关键词
细菌性肝脓肿
病原菌
耐药性
Bacterial liver abscess
Bacterial pathogen
Drug resistance
