摘要
目的分析肝内胆管细胞癌的临床特点及预后相关因素，提高其诊断和治疗水平。方法回顾性分析了1970年1月-2005年1月我院收治的41例肝内胆管细胞癌患者的临床资料。结果41例患者中，行根治性切除18例，1、3、5生存率分别为82．3％、45．8％、45．8％；姑息性切除10例，1、3年生存率分别为11．1％、0；两组相比差异有显著性（x^2=21．38，P〈0．01）。行开腹取活检9例，1、3年生存率分别11．1％、0；与姑息性切除组比较差异无显著性（x^2=0．02，P=0．89）。淋巴结阴性组25例，1、3、5年生存率分别为58．4％、27．3％、27．3％；淋巴结阳性组16例，1、3年生存率分别为61．8％、0；两组相比差异有显著性（x^2=13．85，P〈0．01）。结论肝内胆管细胞癌应以手术治疗为主，根治性手术切除是获得长期生存的唯一途径。
Objective To explore the diagnosis and treatment of the cholangioearcinoma. Methods Forty one patients with cholangioeareinoma who were enrolled in our hospital from January 1970 to January 2005 were retrospectively analyzed. Results Among these 41 patients, the 1,3, and 5-year survival rate was 82.3%, 45.8%, 45.8%, respectively, with radical operation, and was 11.0% , 0, 0 with non-radical operation （x^2 = 21.38, P 〈 0. 01 ）. The 1-year and 3-year survival rate was 11.0% and 0 in 9 patients treated with laparatomy, which was not significantly different from those treated with non-radical operation （x^2 = 0. 02, P = 0. 89）. Four patients did not receive operation and all died within one year. Among 25 patients who did not experience lymph node metastasis, the 1,3, and 5-year survival rate was 58.4%, 27.3%, and 27.3%. Among 16 patients who were found lymph node metastasis, the 1-year and 3-year survival rate was 61. 8% and 0 （x^2 = 13.85, P 〈 0.01 ）. Conclusion Operation is the most effective treatment for cholangioearcinoma. Radical operation is the only curative treatment.
出处
《中国医学科学院学报》
CAS
CSCD
北大核心
2006年第3期332-334,共3页
Acta Academiae Medicinae Sinicae
