摘要
Perilla frutescens(labiatae),as a Chinese traditional and herbal drug with a long history,was determined to consist of abundant bioactive constituents,which make it a potential resource for pharmaceutical(utilization.) The ethyl acetate extract of fresh Perilla frutescens was tested to have a strong antibacterial activity.Four compounds were obtained by column chromatography.The results of antibacterial experiment show that the four compounds all have the activity for inhibiting growth of Staphylowccus aureas and Escherichia Coli.On the basis of chemical and spectral evidences,their chemical structures were determined as 3,3′-diethoxy rosmarinic acid(1),Luteolin(2),Caffeic acid(3), Rosmarinic acid(4).Compound 1 was novel.
Perillafrutescens（ labiatae）, as a Chinese traditional and herbal drug with a long history, was determined to consist of abundant bioactive constituents, which make it a potential resource for pharmaceutical utilization. The ethyl acetate extract of fresh Perilla frutescens was tested to have a strong antibacterial activity. Four compounds were obtained by column chromatography. The results of antibacterial experiment show that the four compounds all have the activity for inhibiting growth of Staphylowccus aureas and Escherichia Coli. On the basis of chemical and spectral evidences, their chemical structures were determined as 3,3＇-diethoxy rosmarinic acid（ 1 ）, Luteolin（2 ）, Caffeic acid（3）, Rosmarinic acid（4）. Compound 1 was novel.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
2006年第7期1292-1294,共3页
Chemical Journal of Chinese Universities
基金
山东省自然科学基金(批准号:Y99B09)
青岛市科技计划项目(批准号:03-2-NN-2)资助
关键词
紫苏
抗菌活性
3
3'-二乙氧基迷迭香酸
Perilla frutescens
Antibacterial activity
3,3＇-Diethoxy rosmarinic acid
