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胸腺素α_1治疗重症肝炎并发自发性细菌性腹膜炎21例 被引量:1

Thymosin α_(1)in the Treatment of 21 Cases of Fulminant Hepatitis Complicated by Spontaneous Bacterial Peritonitis
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摘要 目的研究免疫调节药胸腺素α1治疗重症肝炎并发自发性细菌性腹膜炎的临床效果。方法50例重症肝炎并发自发性细菌性腹膜炎患者,随机分为两组。对照组29例,给予常规治疗。治疗组21例,在常规治疗基础上,给予胸腺素α11.6mg,sc,qd,14d后改为1周2次。观察两组患者临床指标变化及预后。结果治疗组患者与对照组比较,临床症状与体征有效缓解,实验室指标改善,肝、肾功能恢复,生存率提高。结论胸腺素α1可有效治疗慢性重症肝炎并发自发性细菌性腹膜炎,改善患者预后。 Objective To investigate the clinical effects of thymosin α1 on fulminant hepatitis complicated by spontaneous bacterial peritonitis(SBP). Methods Fifty cases of fulminant hepatitis complicated by SBP were divided into two groups,the control group (29 cases) with routine treatment, and the treatment group (21 cases)with both routine treatment and thymosin α1. Results Thymosin α1 could effectively relieve the clinical symptoms and signs, improve the laboratory indexes, restore the functions of the liver and kidney with a rise in the patients' survival rate. Conclusion Thymosin α1 can effectively cure chronic fulminant hepatitis complicated by SBP with improvement in the patient' s prognosis.
出处 《医药导报》 CAS 2006年第7期651-654,共4页 Herald of Medicine
关键词 胸腺素Α1 肝炎 重症 慢性 腹膜炎 细菌性 自发性 Thymosin α1 Chronic fulminant hepatitis Spontaneous bacterial peritonitis
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参考文献6

  • 1中华医学会传染病与,寄生虫病学分会,肝病学分会.病毒性肝炎防治方案[J].中华肝脏病杂志,2000,8(6):324-329. 被引量:14010
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  • 5吴亮,王颖,张振刚,田德英.日达仙治疗重型肝炎临床观察[J].中西医结合肝病杂志,2003,13(6):335-336. 被引量:5
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二级参考文献6

  • 1Kouttab AM, Goldstein AI., Liu M, et al, Production of httman B and T-cell growth factors is enhanced by thymic hormones, Immunopharmacology, 1998, 16: 97 - 105. 被引量:1
  • 2Goldstein AL.Clinical application of Thymosin α1. Cancer Invest,1994, 12:545-547. 被引量:1
  • 3Liao YF. Efficacy of Yhymosin α1 in Patients with chronic Hepatitis B:A Randomized, controlled Trial.Hepatology, 1998, 27: 1383 -1387. 被引量:1
  • 4Kouttab AM, Goldstein AL, Liu M, et al, Production of human B and T-cell growth factors is enhanced by thymic hormones. Immunopharmacology, 1998, 16: 97 -- 105. 被引量:1
  • 5Goldstein AL.Clinical application of Thymosin α1. Cancer Invest,1994, 12:545--547. 被引量:1
  • 6中华医学会传染病与,寄生虫病学分会,肝病学分会.病毒性肝炎防治方案[J].中华肝脏病杂志,2000,8(6):324-329. 被引量:14010

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