摘要
目的:探讨了可溶性白细胞介素-2受体(sIL-2R)和肿瘤坏死因子(TNF-α)水平与原发性肝癌的关系及临床意义。方法:采用ELISA和R IA分别测定41例原发性肝癌患者血清sIL-2R和TNF-α水平。结果:原发性肝癌患者在治疗前血清sIL-2R和TNF-α水平非常显著地高于正常人组(P<0.01),经治疗后3个月与正常人组比较仍有显著性差异(P<0.05)。结论:检测原发性肝癌患者血清sIL-2R和TNF-α水平的变化对临床观察预后有重要的临床价值。
Objective To study the clinical significance of changes of serum levels of soluble interleukin - 2 receptor （ sIL - 2R） and tumor necrosis factor-α （TNF -α） in patients with primary hepatic cancer. Methods Serum sIL- 2R （with ELISA） and TNF - α （ with RIA） levels were measured in 41 patients with primary hepatic cancer both before and 3 months after treatment as well as in 35 controls. Results Before treatment, serum sIL - 2R and TNF - α levels were significantly higher in the patients than those in the controls （P 〈 0.01 ）, Three months after treatment, the serum slL- 2R and TNF-α levels dropped markedly, but still remained significantly higher （ P 〈 0.05 ）. Conclusion Changes of serum slL - 2R and TNF - α levels contents after treatment might be of prognostic value in patient with primary hepatic cancer.
出处
《放射免疫学杂志》
CAS
2006年第3期196-197,共2页
Journal of Radioimmanology
关键词
原发性肝癌
可溶性白细胞介素-2
受体肿瘤坏死因子-α
primary hepatic cancer, soluble interleukin - 2 receptor （ sIL - 2R）, tumor necrosis factor - α
