摘要
目的探讨与分析重度妊娠高血压综合征并发HELLP综合征的发病率、诊断、治疗及预后。方法对我院5年来重度妊娠高血压综合征并发HELLP综合征28例患者的临床资料进行回顾性分析。结果HELLP综合征在重度妊高征患者中的发病率为21.05%,参考美国Tennessee大学制定的诊断标准,完全性HELLP综合征7例,部分性HELLP综合征21例。治疗方法为严密监护母儿情况下积极治疗妊高征,早期使用糖皮质激素,尽快终止妊娠。主要并发症为DIC、胎盘旱剥、肺水肿和急性肾功能衰竭等。28例患者中死亡5例,围产儿死亡11例,死亡率分别为17.86%及39.29%。结论HELLP综合征是重度妊高征的一种严重威胁母儿安全的并发症,及早发现并应用糖皮质激素治疗,可以降低母儿死亡率。
Objective To summarize the incidence, diagnosis, treatment and prognosis of patients with hemolysis, elevated liver enzymes and low platelet count （HELLP） syndrome. Methods The clinical data of fourteen cases with HELLP syndrome complicated by severe pregnancy induced hypertension were analyzed retrospectively during the past five years. Results The incidence of HELLP syndrome was 21.05 % in the patients with severe pregnancy induced hypertension. According to the diagnosis criteria used by Tennessee University, there were seven cases with complete HELLP syndrome and twenty-one cases with partial HELLP syndrome. The major therapeutic ways were intensive maternal and fetal monitoring, active management of preeclampsia and eclampsia, administration of corticosteroids and termination the pregnancy as fast as possible. The major complications were DIC, placental abruption, pneumonedema and acute renal failure. The maternal and perinatal mortality were 17.86 % and 39.29 %, respectively. Conclusion HELLP syndrome was a serious life-threatening complication of severe pregnancy induced hypertension. In order to decrease the maternal and perinatal mortality rate, HELLP syndrome should be diagnosed and treated as fast as possible.
出处
《基层医学论坛（B版）》
2006年第6期486-488,共3页
Public Medical Forum Magazine
关键词
重度妊高征
HELLP综合征
Severe pregnancy induced hypertension HELLP syndrome
