摘要
本文从代谢综合征概念的形成、多个定义的产生到国际糖尿病联盟(IDF)颁布全球统一新定义所经历的几十年的发展历程,对代谢综合征的定义进行了反复的认识,总结了在MS定义认识方面达成的共识,即肥胖、脂代谢异常、高血压、血糖升高或胰岛素抵抗是诊断MS的主要组分,且中央型肥胖作为先决条件。另外,还归纳了对MS有效防治方面的科学思路,即主要的干预手段是采用生活方式改善的和在生活方式改变不足达到目标的情况下,采用针对性药物治疗的次要干预,如降低体重或治疗肥胖、抗高血压、纠正各种脂质异常、控制高血糖等。
This article reviews the viewpoints of multiple professional experts about the concept and definition of metabolic syndrome,rethinks the new International Diabetes Federation （IDF） consensus worldwide definition of the MS. Central obesity,atherogenic dyslipidaemia, hypertension,insulin resistance and hyperglycemia are the main components of metabolic syndrome, and the central obesity is a prerequisite risk factor for the diagnosis of the syndrome in the new definition. Healthy lifestyle promotion is recommended as the primary intervention by the metabolic syndrome by IDF,and healthy lifestyle changes addresses improvement of metabolic syndrome. In addition,drug therapy is supported by clinical trail evidences in people for whom lifestyle changes is not and who are considered to be at high risk for cardiovascular diseases,including weight loss or treat obesity,lower TG, raise HDL-C,reduce LDL-C,antihypertensive therapy and insulin sensitizers.
出处
《继续医学教育》
2006年第29期61-65,共5页
Continuing Medical Education
关键词
代谢综合征
防治
进展
metabolic syndrome
intervention
development
