摘要
目的探讨C反应蛋白(CRP)水平与急性冠状动脉综合征(ACS)预后的关系。方法测定60例ACS患者的CRP,再根据CRP水平分为CRP升高组和CRP正常组,随访6个月。比较两组治疗后再发心绞痛、心律失常、心力衰竭、再梗死和心源性猝死的发生率。结果CRP升高组心绞痛的再发生率46.3%(19/41),心律失常的发生率43.9%(18/41),心力衰竭的发生率9.76%(4/41),再梗死的发生率22.0%(9/41),心源性猝死的发生率7.32%(3/41);CRP正常组心绞痛的再发生率15.8%(3/19),心律失常的发生率10.5%(2/19)心力衰竭的发生率5.3%(1/19),再梗死的发生率5.3%(1/19),无心源性猝死的发生。两组比较有高度显著性差异(P<0.01)。结论CRP在急性冠状动脉综合征的发病机制中起重要作用,而且使ACS后再发心绞痛、心率失常、心力衰竭、再梗死和心源性猝死的发生率明显增高。
Objective To discuss the relationship between C - reactive protein and prognosis of acute coronary syndrome. Methods C - reactive protein of 60 acute coronary syndrome patients was evaluated. The individuals were divided into two groups： One group with higher CRP level and another group with normal CRP level. The following - up duration was 6 months. After correct therapy, the morbidity of re - angina, arrhythmia, heart failure, re - infarction and cardiac death was compared. Results The morbidity of re - angina, arrhythmia, heart failure, re-infarction, cardiac deathwas46.3% （19/41）, 43.9% （18/41）, 9.76% （4/41）, 22.0% （9/41）, 7.32% （3/41） respectively in higher CRP level group; The morbidity of re- angina, arrhythmia, heart failure, re- infarction was 15.8% （3/19）, 10.5% （2/19）, 5.3% （1/ 19）, 5.3% （1/19） respectively in nonnal CRP group and there was no cardiac death accident. There was significant different between the two groups. Conclusions CRP plays an important role in the onset of acute coronary syndrome, and its level is related with the higher morbidity of re - angina, arrhythmia, heart failure, re- infarction and cardiac death.
出处
《医学研究杂志》
2006年第6期66-67,共2页
Journal of Medical Research
关键词
C反应蛋白
急性冠状动脉综合征
预后
C - reactive protein （CRP）
Acute coronary syndrome
Prognosis
