摘要
目的:探讨脑卒中后抑郁对神经功能康复及生活质量的影响,并应用盐酸帕罗西汀(赛乐特)进行抗抑郁治疗。方法:68例脑卒中后抑郁患者随机分为观察组和对照组各34例,均给予系统的康复治疗,观察组患者同时每天口服赛乐特20 mg抗抑郁治疗,对照组口服维生素B1;治疗前后分别采用Zung抑郁状态自评量表、Fugl-Meyer、Barthel指数及生活满意指数A(LSIA)对患者进行评定。结果:治疗6周后抑郁评分,观察组(55.3±13.3)与治疗前(70.6±14.2)及对照组(63.8±13.9)比较显著降低(P<0.01,P<0.05);Fugl-Meyer、Barthel指数及LSIA评分,治疗后2组均有提高,观察组更显著(P<0.01)。结论:改善脑卒中后抑郁状态有利于神经功能康复及生活质量的提高。
Objective：To explore the effects of post-stroke depression on the recovery of neurological function and the quality of life and the effectiveness of seraxat in treatment of depression. Methods. Eighty-six post-stroke depression cases were randomly divided into observation group （n=34） and control group （n= 34）, and they were all subjected to rehabilition therapy, at the same time the patients in the observation group accepted anti-depresssive therapy. All of eases were evaluated according to Self-Rating Depression Scale （SDS）, Fugl-Meyer Motor Assessment, ADL and life satisfaction index A before and after treatment. Results： after treatment the scores of SDS in observation group were lower after treatment than before treatment （P〈0.01） and those in control group （P〈0.01）. The scores of Fugl-Meyer, ADL and LSIA in observation group were higher than those in control group （P〈0.01）. Conclusion： Anti-depresssive therapy may be helpful to rehabilitate neurological function and improve the quality of life.
出处
《中国康复》
2006年第3期170-171,共2页
Chinese Journal of Rehabilitation
关键词
脑卒中
抑郁
神经功能
生活质量
stroke
depression
neurological function
quality of life
