摘要
目的观察NO供体-单硝酸异山梨醇酯结合依沙吖啶应用于中期妊娠引产的临床效果及其安全性。方法研究组于依沙吖啶羊膜腔注射前24h阴道应用单硝酸异山梨醇酯60mg,对照组依沙吖啶羊膜腔注射前无任何处理,比较两组临床结局。结果研究组引产时间及产程均短于对照组,单硝酸异山梨醇酯阴道用药对母体血压及心率均无明显影响,不增加胎盘、胎膜残留率。结论单硝酸异山梨醇酯阴道用药可缩短依沙吖啶引产时间及产程,无明显副作用。
Objective： To study the efficacy and safety of isosorbide - 5 - mononitrate （IMN） combined with Ethacridine in termination of mid- trimester pregnancy. Methods： 120 pregnant wemen were randomly assigned into two groups, the study group and control group. Women in the control group just received injection of 100mg Ethacridine, while women in the study group were inserted 60mg IMN into the posterior fornix 24 hours before injection of Ethacridine. Results： The abortion time and the duration of labour in study group were shorter than that in control group. There was no obviously effect of IMN on maternal blood pressure, heart rate and incidence of retained placenta and fetal membranes. Conclusion： IMN combined with Ethacridine can reduce the abortion time and duration of labour with no obvious side effects.
出处
《中国计划生育学杂志》
北大核心
2006年第6期365-366,共2页
Chinese Journal of Family Planning
关键词
单硝酸异山梨醇酯
依沙吖啶
中期妊娠引产
Isosorbide - 5 - Mononitrate Ethacridine Mid - trimester pregnancy Induced labor
