摘要
研究了一系列联苯衍生物和ＳＯ３在二氯甲烷中进行的磺化反应。联苯的磺化产物为４－磺酸取代物，进一步反应得到４，４′－、２，４，４′－及少量的２，４，２′，４′－多取代物。甲氧基取代的联苯体现了较高的反应活性，３，３′－二甲氧基联苯的彻底磺化得到五磺酸取代产物，２－甲氧基联苯的单磺化主要发生在５位上，４－甲氧基联苯的单磺化先在３位上进行。
The sulfonation of a number of biphenyl derivatives, viz. biphenyl, 2 OMe, 4 OMe, 3,3′ (OMe) 2 , 4,4′ (OMe) 2, 4,4′ (OSO 2Me) 2 with SO 3 was studied. Sulfonation of biphenyl leads to the subsequent formation of the 4 sulfonic acid(4 S), 4,4′ S 2, 2,4,4′ S 3 and traces of 2,4,2′,4′ S 4. The sulfonation of the oxy substituted biphenyls also occurs successively in the one phenyl and then in the other. Further sulfonation of 3,3′ dimethoxy biphenyl yields 2,4,6,4′,6′ S 5. In case of the asymmetrical 2 and 4 methoxybiphenyl the substitution starts in the anisyl moiety.
出处
《合成化学》
CAS
CSCD
1996年第3期261-264,共4页
Chinese Journal of Synthetic Chemistry
基金
国家教委留学回国人员科研基金
关键词
三氧化硫
联苯
衍生物
磺化反应
Aromatic sulfonation, Sulfur trioxide, Biphenyl derivatives.
