摘要
目的:研究以无GnRH-a降调激素替代作为子宫内膜准备方式对冻融胚胎移植(FET)临床妊娠率和胚胎植入率的影响。方法:对我中心进行的88个以无GnRH-a降调激素替代(A组)和hMG促排(B组)两种方法进行子宫内膜准备的FET周期进行回顾性分析,比较组间移植日子宫内膜厚度以及临床妊娠率、胚胎植入率的差异。结果:A组32个周期,共移植91枚胚胎,胚胎植入率13.19%,临床妊娠率31.25%(10/32);B组56周期,共移植156枚胚胎,胚胎植入率15.48%,临床妊娠率32.14%(18/56)。两组移植日子宫内膜厚度、临床妊娠率和胚胎植入率等方面均无统计学差异(P>0.05)。结论:无GnRH-a降调激素替代、hMG促排作为FET子宫内膜的准备方式,得到的FET临床妊娠率和胚胎植入率无差异。
Objective： To analyze non-GnRH-a down-regulated hormone treatment therapy （HRT） as endometrial preparation protocols influencing the clinical pregnancy rate and implantation rate following frozenthawed embryo transfer （FET） cycles. Methods： A retrospective study was carried out from 88 FET cycles using either non-GnRH-a down-regulated HRT （group A） or hMG stimulation （group B） as endometrial preparation protocol. Endometrial thickness, clinical pregnancy rate and implantation rate, ect. were compared. Results： In group A, 12 （13.19%） embryos of 32 cycles were implanted and 10 （31.25%） clinical pregnancies were established, while in group B, 24 （15.48%） embryos of 56 cycles were implanted and 18 （32.14%） clinical pregnancies were established. No significant differences were found within age, number of transferred embryo, embryo stage, CES, endometrial thickness （P〉0.05） between two groups. Clinical pregnancy rate and implantation rate did not differ significantly either （P〉0.05）. Conclusion： Clinical pregnancy rate and implantation rate in FET cycles did not differ due to different endometrial preparation protocols： non-GnRH-a down-regulated HRT and hMG stimulation.
出处
《生殖与避孕》
CAS
CSCD
北大核心
2006年第6期344-347,共4页
Reproduction and Contraception
关键词
冻融胚胎移植
激素替代
HMG
控制性促排卵
临床妊娠率
胚胎植入率
frozen-thawed embryo transfer
hormone repl,icement therapy
hMG
controlled ovary stimulation
clinical pregnancy rate
implantation rate
