摘要
首先以EDS76-NE_4和EDS76-BC两个毒株的鸭胚培养物混合或单独分别接种鸡,证明混合接种的鸡,其HI价高于单独接种的鸡。应用混合培养物(HA价≥1∶32768)制成3批灭活油佐剂EDS76疫苗,接种鸡6万只以上,接种鸡未出现不良反应,接种后15、21、35和60天时,鸡的平均HI价分别为7.5、8.3、9.3和8.0。
Abstract As it had been demonstrated initially that an inoculum composed of the inactivated duck embryos mixtured culture of both the EDS76-NE4 and the EDS76-BC induced a higher HI titer in checkens than that induced by either of these two only, three lots of inactivated oil adjuvant vaccine were produced with this virus cultures mixture, which would produced a HA titer>1: 32768. More than 60,000 chicks were vaccinated with this experimental vaccine and no unexpected reaction expressed by chicks was observed. The mean HI titers at the 15, 21,35 and 60 days following vaccination were 7.5,8.3, 9.3 and 8.0 respectively.
出处
《中国兽药杂志》
北大核心
1996年第3期17-19,共3页
Chinese Journal of Veterinary Drug