摘要
[目的]观察补肾密骨片结合经皮自体骨髓移植对骨折延迟愈合治疗后的骨密度和生物力学性能影响。[方法]预制新西兰大耳白兔骨延迟愈合模型,将75只兔随机分为四组:A组20只,饲料中加入补肾密骨片,骨延迟愈合区注入自体红骨髓2 m l;B组20只,饲料中加入补肾密骨片,骨延迟愈合区不注入自体红骨髓;C组20只,饲料中不加补肾密骨片,骨延迟愈合区注入自体红骨髓;D组15只,造成骨延迟愈合模型后,饲料中不加补肾密骨片,骨延迟愈合区不注入自体红骨髓。治疗后12周处死动物取材,行骨密度及生物力学测试。[结果]骨密度及生物力学测试均显示A组骨愈合优于B、C、D组。[结论]补肾密骨片结合经皮自体骨髓移植治疗骨折延迟愈合的骨组织的骨密度及生物力学强度优于单一骨髓移植或中药治疗。
[ Objective] To study the effect of Chinese traditional medicine and bone marrow transplantation on treating delayed union. [ Method]The model of delayed union in 75 rabbits was made and divided into 4 groups. Group A, 20 rabbits treated with Chinese traditional medicine and red marrow 2 ml ; Group B, 20 rabbits treated with Chinese traditional medicine ; Group C, 20 rabbits treated with red marrow; Group D, 15 rabbits treated with nothing. X-ray in the 4th, 8th and 12th weeks were observed after treating. And bone mineral density and biomechanics were observed in 12ts week after trenting. [ Result] X-ray revealed that group A heal earlier than group B, C and D. At the same time, bone mineral density and biomechanics in group A was better than others. [ Conclusion] The treatment of delayed union by Chinese traditional medicine and bone marrow transplantation is one of effective means.
出处
《中国矫形外科杂志》
CAS
CSCD
北大核心
2006年第12期918-920,共3页
Orthopedic Journal of China
关键词
中药
中医治疗
骨髓移植
骨折延迟愈合
骨密度
生物力学
Chinese herbal medicine
Chinese medicine treatment
Bone marrow transplantation
Delayed union
Bone mineral density
Biomechanics
