摘要
选用２４只２月龄ＳＤ处女鼠配对分组，实验组日粮添加１０μｇ／ｇ塞曼特罗（ＣＩＭ），试验期３０天。与对照组比较，ＣＩＭ显著提高大鼠生长速度（２７．３０％，Ｐ＜０．０１）和胴体比率，降低腰胁部脂肪重，提高腓肠肌、比目鱼肌和趾浅屈肌的鲜重和ＲＮＡ合量及ＰＮＡ／ＤＮＡ值，同时提高大鼠垂体和血清ＧＨ水平分别达３６．７０％（Ｐ＜０．０１）和２３．７７％（Ｐ＜０．０５），降低血清脲氮含量。表明ＣＩＭ可显著促进大鼠生长，降低体脂含量，促进肌肉肥大，促进蛋白沉积。其作用机理可能还与其促进ＧＨ的合成和分泌有关。
Twenty four two-month-old virgin Sprague-Dawley rats were used to evaluate the effect of cimaterol (CIM) on growth pattern, biochemical characteristics of selected muscles and hormone level by using a pair design. Rats were alloted by weight to two groups which were ad libitum fed a diet containing 0 or 10 μg / g CIM. The experiment lasted 30 days and rats were weighted every ten days. During the experiment time 10μg/ g CIM improvedgrowth rate and carcass yield, whereas the weight of the subcutaneous waist fat pad was decreased. The results show that CIM can significantly improve growth performance and reduce body fat content in rat. By the end of the study, compared to 0μg / g, 10μg / g CIM significantly increased the weight and RNA concentration of gastrocnemius (fast-twitch),soleus (slow-twitch) and flexor digitalis pedis superficials (mixed) while decreased DNA concentration. As a result, the ratio of RNA / DNA of the three muscles increased significantly.This implies that the growth of the muscles is through muscle hypertrophy and thefast-twitch muscle is more sensitive to CIM. Dietary CIM also increased pituitary and serum GH content while decreased urea nitrogen level. This suggests that CIM plays its role partially by regulating the endogenous GH secretion in rat.
关键词
塞曼特罗
大鼠
生长
胴体
生长激素
家畜生理
Cimaterol, Rat, Growth, Carcass characteristics, Growth hormone
