摘要
Objective： To investigate the effects of acupuncture and combined acupuncture and medicine on the quality of life and the genital endocrine level in postmenopausal women. Methods： Forty-seven patients were randomly assigned to acupuncture and acupuncture plus medicine groups, 23 cases in the acupuncture group and 24 cases in the acupuncture plus medicine group. The observed course of treatment was 3 months. A Chinese concise SF 36 questionnaire was used to evaluate the quality of life in the different groups of patients before and after treatment. Meanwhile, radioimmunoassay was used to observe the differences in serum genital hormones： follicle stimulating hormone （FSH）, luteinizing hormone （LH） and estradiol （E2） contents between pretreatment and posttreatment in both groups. Results： After treatment, there was a significant difference in quality of life between the two groups and it was better in the acupuncture plus medicine group than in the acupuncture group（P〈 0.01）. E2 content increased more markedly in the acupuncture plus medicine group than in the acupuncture group（P〈 0.05）. There were no significant differences in FSH and LH contents between the two groups（P 〉 0. 05）. Conclusion. Both acupuncture and acupuncture plus medicine can improve the quality of life and increase obviously low E2 content in postmenopausal women. Acupuncture plus medicine raises the patients＇ quality of life and E2 content more markedly than acupuncture. It is suggested that both acupuncture and acupuncture plus medicine can improve the symptoms, signs, and physical and mental health, raise the quality of life and ameliorate genital-endocrine environment in postmenopausal women, but a combination of acupuncture and medicine has a better effect.
目的:观察针刺、针药结合对绝经后女性生存质量及生殖内分泌水平影响。方法:将47例患者,随机分配至针利组和针药组,针刺组23例,针药组24例,3个月为一观察疗程。采用简明SF-36中文版问卷方式,对各组患者进行治疗前后生存质量调查,同时,采用放免技术,观察治疗前后两组患者血清中生殖激素卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E_2)含量变化。结果:治疗后两组生存质量总体比较差异显著,针药组优于针刺组(P<0.01);针药组 E_2含量提高较针刺组显著(P<0.05),FSH、LH 含量变化两组差异不显著(P>0.05)。结论:针刺、针药皆能改善绝经后女性的生存质量及提高患者明显低下的 E_2含量水平,针药治疗对患者的生存质量、E_2含量提高较针刺治疗显著,提示针刺、针药皆能改善绝经后女性的症状、体征及身心健康状况,提高生存质量,改善生殖内分泌环境,针药结合效果尤佳。
