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三种达必佳降调方案用于体外受精-胚胎移植的效果比较 被引量:1

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摘要 目的比较3种达必佳垂体降调节方案在IVF-ET中的效果.方法回顾分析2004年6至2005年11月本中心在84个IVF-ET长方案周期中采用3种短效达必佳降调方案的病历资料.3组各28例,达必佳用法均为隔日注射1支(0.1mg/支).其中,1组达必佳在注射hCG日前停药(总量5~7支/周期);2组达必佳用至注射hCG日停药(总量8~12支/周期);3组根据卵泡数及生长速度决定达必佳停药时间(总量3~7支/周期).结果 3组周期获卵数、受精率、胚胎种植率及临床妊娠率比较差异无显著性(P>0.05).1组较2、3组发生早发LH峰及取消周期数增加,胚胎冷冻率下降.2组较1、3组应用达必佳时间及总量多,使用促性腺激素少,受精率高(P<0.05),无卵巢抑制发生.3组应用达必佳时间明显缩短,虽使用促性腺激素较多,但临床妊娠率与2、3组接近,发生早发LH峰率和取消周期数低于1组.结论 2、3组改良降调方案优于1组.小剂量达必佳用药也应个体化.
出处 《遵义医学院学报》 2006年第1期43-45,共3页 Journal of Zunyi Medical University
基金 贵州省科技厅攻关课题基金黔科合计(2001)1214
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