摘要
本研究应用电生理结合微机系统处理方法，以消化间期综合肌电为指标，观察并记录了给清醒、健康、空腹犬以１００％枳实浓缩液（１ｍｌ／ｋｇ）灌胃后产生的增强小肠电活动的效应，可被胆碱能受体阻断剂阿托品明显抑制，表现为Ⅱ相和总周期虽有延长，但Ⅱ、Ⅲ相及总周期内平均每簇中快波数均减少，每分钟快波数也减少，提示枳实的作用可能与Ｍ受体有关。
Effect of Fructus Aurantii Immaturus(FAI) was observed by using the computerized electrophysiologic method with the interdigestive myoelectric complex(IDMEC) as criterion. 100% FAI was given to the healthy, awakened and fasting dogs by gastrogavage and as soon as the effect on electric activity of small intestine appeared, atropine was injected. Results showed that the enhancing effect of FAI could be inhibited significantly by atropine, an antagonist of cholinergic receptor.It revealed that although the duration of phase Ⅱ and general cycle were prolonged, but the spike burst per cluster in the duration between phase Ⅱ and phase Ⅲ as well as that per minute were decreased. It suggested the effect of FAI might be relevant with muscarinic receptor.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
1996年第5期292-294,共3页
Chinese Journal of Integrated Traditional and Western Medicine
基金
国家自然科学基金
关键词
枳实
阿托品
小肠
动作电位
Fructus Aurantii Immaturus, atropine, small intestine, action potential
