摘要
目的:探讨病毒性心肌炎(VMC)患者血清肿瘤坏死因子(TNF-α)、白细胞介素1(IL-1)、白细胞介素6(IL-6)的变化及黄芪注射液防治作用。方法:治疗组24例用黄芪注射液治疗,对照组24例用辅酶A、ATP等治疗。结果:治疗后治疗组血清TNF-α、IL-1和IL-6水平显著下降(P<0.01),与健康组无显著差异;对照组治疗前后TNF-α、IL-1和IL-6水平无差异,并显著高于健康组(P<0.01)。结论:黄芪注射液可降低TNF-α、IL-1和IL-6,对病毒性心肌炎有良好的防治作用。
Objective ： To study on changes of serum TNF - α, IL - 1 and Il - 6 in viral myocardies and effect of astragalus injection on viral myocarditis （VMC） patients. Methods The serum levels of TNF -α, IL- 6and IFN -γ in various stages （before and after therapy） of the test and control team of VMC patients and health teame were detected by radioimmunoassay and ELISA assay. Rsults The serum eyokines levels increased significantly in VMC patients than health team （P 〈 0. 01 ） ;those of test team decreased significantly after treatment by astragalus injection （ P 〈 0. 01 ） ; those of control team no significantly changed between before and after treatment. Conclusion The astragalus injection could decrease significantly TNF - α, IL - 1 and IL - 6 serum level of VMC patients and had obvious functiions of nrevention and treatmet.
出处
《实用中医药杂志》
2006年第6期329-330,共2页
Journal of Practical Traditional Chinese Medicine
