期刊文献+

叶酸在结肠癌发生发展和防治中作用的研究进展 被引量:1

原文传递
导出
摘要 叶酸是一种水溶性维生素,与DNA合成、修复及稳定密切相关.近来国外许多研究发现叶酸缺乏与结肠癌发生关系密切,补充叶酸可降低结肠癌发生率.本文主要对叶酸的生理作用、叶酸缺乏与结肠癌发生机制及叶酸防治结肠癌应用现况等方面作一综述.
出处 《中华消化杂志》 CAS CSCD 北大核心 2006年第4期282-283,共2页 Chinese Journal of Digestion
  • 相关文献

参考文献15

  • 1Giovannucci E,Chen J,Smith-Warner SA,et al.Methylenetetra-hydrofolate reductase,alcohol dehydrogenase,diet,and risk of colorectal adenomas.Cancer Epidemiol Biomarkers Prev,2003,012:970-979. 被引量:1
  • 2Rampersaud GC,Kauwell GP,Hutson AD,et al.Genomic DNA methylation decreases in response to moderate folate depletion in elderly women.Am J Clin Nutr,2000,72:998-1003. 被引量:1
  • 3Kim YI.Folate and DNA methylation:a mechanistic link between folate deficiency and colorectal cancer? Cancer Epidemiol Biomarkers Prev,2004,13:511-519. 被引量:1
  • 4Duthie SJ,Narayanan S,Brand GM,et al.Impact of folate de ficiency on DNA stability.J Nutr,2002,132:2444S-2449S. 被引量:1
  • 5Choi SW,Mason JB.Folate and carcinogenesis:an integrated scheme.J Nutr,2000,130:129-132. 被引量:1
  • 6Nagothu KK,Rish AK,Jaszewski R,et al.Folic acid-mediated inhibition of serum-induced activation of EGFR promoter in colon cancer cells.Am J Physiol Gastrointest Liver Physiol,2004,287:G541-G546. 被引量:1
  • 7Pufulete M,Al-Ghnaniem R,Khushal A,et al.Effect of folic acid supplementation on genomic DNA methylation in patients with colorectal adenoma.Gut,2005,54:648-653. 被引量:1
  • 8Crott JW,Choi SW,Ordovas JM,et al.Effects of dietary folate and aging on gene expression in the colonic mucosa of rats:implications for carcinogenesis.Carcinogenesis,2004,25:69-76. 被引量:1
  • 9Choi SW,Friso S,Dolnikowski GG,et al.Biochemical and molecular aberrations in the rat colon due to folate depletion are age-specific.J Nutr,2003,133:1206-1212. 被引量:1
  • 10朱舜时,Joel Mason,施尧,胡运彪,李蓉蓉,汪敏,周怡和,金冠球,谢宇野,邬桂泉,夏德凰,钱珍华,宋海连,屠伯强,张丽冬,Robert Russell,萧树东.叶酸对胃癌和其他胃肠道癌发生的干预作用──临床试验七年随访[J].胃肠病学,2002,7(2):73-78. 被引量:51

二级参考文献31

  • 1周连鸿,吴裕炘,施尧,江绍基,萧树东,吴云林,袁耀宗,瞿祖康,王秀玲,宗春华,马菊珍,汪敏,鲍继桂,张金龙.叶酸及硒酵母对慢性胃炎的萎缩,肠化及非典型增生的疗效观察[J].中华消化杂志,1993,13(4):217-219. 被引量:23
  • 2朱舜时,李蓉蓉,施尧,燕善军,袁济民,萧树东,江绍基.胃癌患者胃粘膜细胞内维生素的变化[J].中华消化杂志,1994,14(1):28-30. 被引量:16
  • 3Mason JB.Folate and colonic carcinogenesis: searching for a mechanistic understanding.J Nutr Biochem,1994,5: 170~175. 被引量:1
  • 4Cravo ML,Mason JB,Dayal Y,Hutchinson M,Smith D,Selhub J,Rosenberg IH.Folate deficiency enhances the development of colonic neoplasia in dimethylhydrazine-treated rats.Cancer Res,1992,52: 5002~5006. 被引量:1
  • 5Giovannucci E,Stampfer MJ,Colditz GA,Hunter DJ,Fuchs C,Rosner BA,Speizer FE,Willett WC.Multivitamin use,folate,and colon cancer in women in the Nurses' Health Study.Ann Intern Med,1998,129: 517~524. 被引量:1
  • 6Xiao SD,Meng XJ,Shi Y,Hu YB,Zhu SS,Wang CW.Interventive experimental study of high-dose folic acid in gastric carcinogenesis in beagles.Gut,2001 (submitted). 被引量:1
  • 7Whitehead R.Mucosal biopsy of the gastrointestinal tract.In Whitehead R.eds.Major problems in pathology.Saunders co.Philadelphia,London,Toronto,1979: 1~69. 被引量:1
  • 8Wilson SD,Horne DW.Use of glycerol-cryoprotected lactobacillus casei for microbiological assay of folic acid.Clin Chem,1982,28: 1198~1200. 被引量:1
  • 9Bieri JG,Brown ED,Smith JC.Determination of individual carotenoids in human plasma by high performance liquid chromatography.J Liq Chromatogr,1985,8: 4473~4484. 被引量:1
  • 10徐采朴 刘为纹.慢性胃炎、肠化和不典型增生的随访观察[J].中华消化杂志,1984,4:10-12. 被引量:1

共引文献50

同被引文献10

引证文献1

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部