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回顾性分析治疗中重度妊高征的用药原则与时机

Retrospective analysis of opportunity and medicinal principal in the treatment of moderate and severe pregnancy induce hypertension
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摘要 目的了解治疗中重度妊高征的时机与用药原则。方法收集本院2002-09—2004-04、住院分娩的255例妊高征患者,按轻、中、重度分组。其中:中重度妊高征患者152例,再按单用硫酸镁治疗组和硫酸镁加用其他降压药物治疗组,分析2组围生儿体重、Apgar评分及死胎率的情况。结果对中度妊高征患者,单用硫酸镁与同时再加用降压药物治疗,2组比较对围生儿窒息无差异;但对重度妊高征患者改善围生儿窒息情况有积极意义。结论重度妊高征用硫酸镁加用降压药物治疗,对改善新生儿Apgar评分及死胎率有积极意义。 Objective To retrospective analyse the opportunity and medicinal principal in the treatment of moderate and severe pregnancy induce hypertension(PIH). Methods Hopitalization 225 patiens with PIH during NOV. 2002 to FIR. 2004 were collected. PIH patiens were classified according to gently moderate and severe. Then 152 patiens with svere PIH were divided two groups by used differenct drugs: Ⅰ group ( magnesium sulfate) and Ⅱ group ( magnesium sulfate + decompression drug). The Neonate body weight , Apgar score and rate of fetal death were compared with the two group. Results There are not notable difference bettween two group of neonate body weight, rate of fetal death and Apgar score. Apgar score in severe PIH is notable lower than other groups, but there are not notable difference bettween two group of neonate body weight and rate of featal death. Conclusion Magnesium sulfate and decompression drugs can be used to therapy severe PIH patiens and improve the Apgar score and rate of fetal death of the neonate.
作者 于洁 冯欣
出处 《中国临床药理学杂志》 CAS CSCD 北大核心 2006年第2期106-108,共3页 The Chinese Journal of Clinical Pharmacology
关键词 妊高征 新生儿窒息 降压药 pregnancy induce hyertension intrauterine death decompression drugs
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