摘要
目的 :评价雷帕霉素药物涂层支架 (CYPHERCordis)治疗冠脉支架内再狭窄的临床效果。方法 :我院在 2 0 0 2年 10月至 2 0 0 3年 10月对 2 1例冠心病冠脉支架内再狭窄患者置入CYPHERTM支架(Cordis)治疗 ,对 16例前降支支架内再狭窄患者置入CYPHER支架 16个 ,4例右冠支架内再狭窄患者置入CYPHER支架 4个 ,1例回旋支支架内再狭窄患者置入CYPHER支架 1个。观察药物涂层支架的手术成功率 ,术中并发症 ,住院期间及 2 14个月随防期间的心绞痛、心肌梗塞、猝死 ,再次血运重建等发生情况。结果 :手术即刻成功率 10 0 % ,术后造影病变残余狭窄率为 5 %± 3 5 % ,支架完全覆盖病变 ,支架近远段无新夹层 ,血流TIMI3级 ,临床随访 2～ 14个月 2 1例心绞痛消失 ,其中 12例 6～9个月 ,复查冠脉造影 ,无支架内再狭窄发生。结论 :雷帕霉素药物涂层支架 (CYPHER) ,治疗冠脉支架内再狭窄是安全有效的 。
Objective To evaluate the clinicat effect of CYPHERTM （rapamycin）stent in treatment of coronary instent restenosis. Methods from October 2002 to october 2003. 21patients with coronary heart disease in-stent restenosis were treated with CYPHERTM （cordis）stent and 16 stents were planted in 16 Lefe anterior descending artery （LAD）in-stent restenosis 4 stents were planted in 4 right coronary artery （RCA）in-stent restenosis. 1. stent was planted in 1 left circumflex artery （LCX）in-stent restenosis, we observed the procedure success and conplication rates, The occurance of angina, myocardial infarction, sudden death, the revascularization rate during the inhospital and 2 - 14 months follow up. Results immediate procedure success rate was 100%with residual stenosis of 5.0% ± 3.5%. All the lesions were covered fully by stents and the coronary flow reached TIMI guade three. No new dissection was observed in the optimal of stents. During the 14 months follow-up, the sympton of angina was disappeared in 21 patiants. 12 Patients receivtd coronary artery angiography in 6 - 9months and no restenosis was ohserved. Conclusion Druy eluting stent （CYPHERTM）implantation is a safe and efficient therapy in treating patients with in-stent restenosis angioplasty and the first generat coronary stents.
出处
《中国分子心脏病学杂志》
CAS
2004年第1期29-31,共3页
Molecular Cardiology of China
