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牙周基础治疗后龈沟液中TNF-α的变化 被引量:12

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摘要 目的:探讨牙周基础治疗对龈沟液中肿瘤坏死因子α(TNF-α)水平的影响。方法:选取成人牙周炎位点87个,用夹心ELISA法进行龈沟液TNF-α水平的检测并记录相关临床指标,然后行牙周基础治疗,治疗后6周再次检测观察龈沟液中TNF-α水平及相关临床指标,比较牙周基础治疗前后龈沟液中TNF-α及相关临床指标的差异。结果:牙周基础治疗前后探诊深度(PD)、附着丧失(AL)及龈沟液中TNF-α水平差异均有显著性(P<0.05),龈沟液量、菌斑指数(PLI)和改良龈沟出血指数(mBI)有非常显著性改善(P<0.01)。结论:牙周基础治疗在降低各项临床指标的同时对龈沟液中TNF-α水平也有明显影响,确实有控制牙龈炎症的作用。
出处 《实用医学杂志》 CAS 2006年第10期1146-1147,共2页 The Journal of Practical Medicine
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