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亚低温治疗急性脑梗死的临床观察 被引量:3

Therapeutic effect of mild-hypothermia for patients with severe brain infarction.
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摘要 目的探讨亚低温治疗重症急性脑梗死的临床疗效,以及红外线光照法复温方式对预后的影响。方法发病24 h内入院的84例急性脑梗死患者,随机分为对照组21例,亚低温治疗组63例,其中自然复温37例,红外线光照复温26例。治疗后1个月进行神经功能缺损评分。结果亚低温治疗组治疗后神经功能缺损评分改善明显好于对照组,有显著性差异(P<0 05)。亚低温光照复温组体温、心率、血压回复平稳,血小板计数、颅内压较自然复温组低有统计学差异(P<0 05),但脑疝发病率无统计学差异(P>0 05)。结论亚低温治疗技术明显促进重症急性脑梗死患者的神经功能恢复,降低死亡率。光照复温是良好的复温方式。 Objective To study the therapeutic effect of mild - hypothermia for severe brain infarction and the influence of infrared ray radiation rewarming on outcome of the patients. Methods Eighty - four patients with brain infarction to be adimitted within 24 hours after the onset of symptom were randomly assigned to control group( n =21 ) and hypothermia group( n =60), the hypothermia group patients were further divided into two groups according to the rewarming method: infrared ray radiation rewarming group( n =26 ) and natural rewarming group( n =37 ). One month later patients were evaluated by use of Neurological Deficit Scale score. Results According to the neurological Deficit Scale score, hypothermia group patients'outcomes were significantly better than those of control group( P 〈 0.05 ). Infrared ray radiation rewarming group patients body temperature, heart rate and blood pressure recovered steadily, platelet count and intracranial pressure were significantly lower than those of natural rewarming group patients( P 〈 0.05 ). But there was no significant difference in incidence of cerebral hernias between two groups( P 〉 0. 05 ). Conclusion Mild hypothermia can accelerate the recovery of the nerve function and reduce the mortality of patients with severe brain infarction. Infrared ray radiation rewarming is a good way of rewarming.
出处 《临床和实验医学杂志》 2006年第5期466-467,共2页 Journal of Clinical and Experimental Medicine
关键词 亚低温治疗 脑梗死 光照复温 Mild- hypothermia Brain infarction Infrared ray radiation rewarming
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参考文献7

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