摘要
目的:观察岩舒注射配合肝动脉化疗栓塞治疗中晚期原发性肝癌的疗效。方法:将68例中晚期原发性肝癌患者随机分为两组:治疗组35例,用岩舒注射液配合肝动脉化疗栓塞治疗;对照组33例,单纯用肝动脉化疗栓塞治疗。结果:治疗组与对照组的近期有效率分别为34.3%和27.3%(P>0.05),KPS评分改善有效率分别为65.7%和30.3%(P<0.05)。治疗组在肝功能损害、上腹疼痛、食欲下降及发热的发生率均明显低于对照组,差异有显著性统计学意义(P<0.05),而白细胞下降和恶心、呕吐的发生率略低于对照组,差异无显著性统计学意义(P>0.05)。结论:岩舒注射液配合肝动脉化疗栓塞治疗中晚期原发性肝癌,可提高患者生活质量,减轻不良反应,值得临床推广使用。
Objective： To observe the efficacy of Yanshu injection combined with transcatheter arterial chemoembolization （ TACE ） in treatment of advanced primary hepatic carcinoma （ HC ）. Method：68 patients with advanced HC were randomized into two groups：treatment group of 35 cases with Yanshu injection and TACE and control group of 33 cases with TACE alone. Result： Effective rate was 34.3% and 27.3% （ P 〉 0.05 ）, rate of KPS improvement was 65.7% and 30.3% （ P 〈0.05 ）, of treatment group and control group respectively. Frequencies of hypohepatia, epigastric pain, poor appetite and fever were much lower （ P 〈 0. 05 ）, and of leukocytopenia and vomiting, a little lower （ P 〉 0.05 ）, in treatment group, than those of control group. Conclusion： In treatment of patients with advanced HC, Yanshu injection with TACE could improve quality of life and reduce adverse effect, so as to deserve wider application.
出处
《河北医学》
CAS
2006年第5期443-445,共3页
Hebei Medicine
关键词
岩舒注射液
肝动脉化疗栓塞
原发性肝癌
Yanshu injection
Transcatheter arterial chemoembolization
Primary hepatic carcinoma
