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原发性脑内恶性淋巴瘤的MRI诊断

MRI in diagnosis of primary intracerebral malignant lymphoma
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摘要 目的:探讨脑内原发性恶性淋巴瘤的MRI表现特征,以提高其诊断的正确率。方法:回顾分析10例经病理证实的脑内原发性恶性淋巴瘤MRI表现。结果:10例中单发病灶2例,多发病灶8例,共检出病灶35个,分别位于额叶、顶叶、胼胝体、基底节、小脑半球、小脑蚓。病灶可有不同程度水肿及占位效应,MRI平扫T1WI多呈稍低信号,T2WI呈等或稍高信号,FLAIR呈稍高或高信号,DWI多为稍高或高信号,亦可为等信号。增强扫描病灶多为明显均匀或欠均匀结节、团块样强化,少数为环形强化,可有“缺口征”、“尖角征”。结论:脑内原发性恶性淋巴瘤MRI表现有一定特征,认真分析其影像表现,可提高其诊断准确性。 Objective: To investigate MRI features of primary intracerebral malignant lymphoma (PICML), Methods: MRI findings in 10 patients with pathologlcally-proved PICML were retrospectively analyzed. Results : 35 lesions were identified in 10 patients, single lesion was seen in 2 and multiple lesions in 8, 13 lesions located in the deep white matter, 2 in the callus corpus, 10 in the cerebellum, 1 in the brain stem and 6 in the surface. The lesions presented as node or mass in shape with slight preitumorous edema and mass effect. On plain MRI scans, all lesions presented as iso-or slight hypointense on T1W1, while all lesions presented as iso-or slight hyperintcnse on T2W1 and slight hyperintense or hyperinrensc on FLAIR, most of the lesions presented as slight hy perintense or hyperintense on DWI. Obvious homogenous mass-llke or nodular cnhancement were seen on Gd-DTPA enhanced MRI, 4 presented as "incision sign" and "angular sign". Conclusion : Primary in- tracerebral malignant lymphorna has features on MRI images, correct diagnosis can be made in most cases when imaging findings are combined with clinical information.
出处 《皖南医学院学报》 CAS 2006年第2期137-139,共3页 Journal of Wannan Medical College
关键词 淋巴瘤 磁共振成像 脑肿瘤 Iymphoma magnetic resonance imaging brain neoplasm
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