摘要
在室温下,以对氯邻硝基苯胺邻叔丁基对甲基苯酚和亚硝酸钠为原料通过固相重氮偶合反应一步合成了2-硝基-4-氯-2′-羟基-3′-特丁基-5′-甲基偶氮苯。反应时间15 m in,产率达93%。以HPLC分析,其纯度>99%,并用IR和UV光谱等对其结构进行了表征和确认。
2-Nitro-4-chloro-2′-hydroxy-3′-t-butyl-5′-methyl-azobenzene was synthesized via diazo coupling reaction in solid phase with 4-chlor-2-nitroaniline, 2-t-butyl-4-methyl phenol and sodium nitrite at room temperature. The reaction was completed through one-step method within 15min in a yield of 93% with a higher than 99% purity（by HPLC）, and the structure of the compound was comfirmed by IR and UV.
出处
《应用化学》
CAS
CSCD
北大核心
2006年第5期579-580,共2页
Chinese Journal of Applied Chemistry
关键词
硝基氯羟基特丁基甲基偶氮苯
固相合成
重氮偶合
nitro-chloro-hydroxy-t-butyl-methyl-azobenzene,solid phase synthesis, diazo coupling reaction
