摘要
目的描述误吸性肺损伤(AILI)的胸部影像学特征,探讨应用甲基强的松龙对患者预后的影响。方法回顾性分析具有完整病例资料的16例AILI患者的临床资料,重点分析胸部螺旋CT的表现,比较甲基强的松龙干预前后病变的转归。结果在16例AILI患者中,12例接受有创呼吸支持,均有直接的证据提示存在误吸;胸部螺旋CT检查,病变以肺下叶为主,常多肺叶累及;病变形态以混合性病变多见(14例),渗出/实变10例、网格样/蜂窝肺10例、胸腔积液8例、条索样病变5例、毛玻璃样改变3例。接受甲基强的松龙治疗的8例患者,AILI得到明显缓解,与未接受甲基强的松龙治疗的患者相比,差异有显著性(P<0.01)。结论提高对AILI的识别,早期应用类固醇干预可改善AILI的预后。
Aim To study the spiral CT features and assess the application of methylprednisolone in accidentally inhalation-induced lung injury（AILI）. Methods The imaging findings of 16 patients with AILI were retrospectively analyzed. All the patients had a complete set of chest spiral CT. Focusing on the CT features and the treatment of methylprednisolone, the chest CT was reviewed and the dynamic imaging changes were followed up. Among 16 cases, 12 patients with AILI accepted hurtful ventilator,who had the direct evidence of accidentally inhalation. Rusults Imaging findings of AILI were various. Multi-sited involvement is often seen, and lower lung field is more easily affected than upper lung field. The mixed lesions were normal characters（ n = 14） ,exsudations/consolidations（ n = 10） ,accompanied with interstitial as mesh or irregular linear shadows or honeycomb lungs （ n = 10）, pleural effusions （ n = 8 ）, stripes （ n = 5 ）, and multiple patchy ground-glass shadows（ n = 3 ）. Compared with controls, a significant remission in methylprednisolone controls were found （P 〈 0.01 ）. Conclusion It is recommended that clinicians should improve their understanding of clinical and thoracic imaging of AILI and make a definite diagnosis. At early stage,AILI can be effectively treated by methylprednisolone.
出处
《安徽医药》
CAS
2006年第5期350-352,共3页
Anhui Medical and Pharmaceutical Journal
关键词
误吸
肺损伤
螺旋CT
甲基强的松龙
accidentally inhalation
pulmonary injury
spiral CT
methylprednisolone
