期刊文献+

老年不稳定性心绞痛患者冠状动脉支架置入术后血清瘦素水平变化及奥扎格雷对其的影响

下载PDF
导出
摘要 目的探讨老年不稳定性心绞痛(UAP)患者冠状动脉支架植入术(PTCA)术后血清瘦素(LP)的变化及奥扎格雷对其的影响。方法采用酶联免疫法测定老年UAP患者及PTCA术后即刻、24 h、奥扎格雷治疗15 d血清LP水平。结果老年UAP患者血清LP水平明显高于正常对照组(P<0.05),PTCA术后即刻、24 h血清LP水平明显高于非PTCA组(P<0.05),奥扎格雷治疗15 d血清LP水平明显降低(P<0.01)。结论LP参与了老年UAP病理过程,PTCA可使血清LP水平进一步升高。奥扎格雷可逆转这一变化。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2006年第4期465-466,共2页 Chinese Journal of Gerontology
  • 相关文献

参考文献9

二级参考文献34

  • 1Zhang Y,Proenca R,Maffei M,et al.Positional cloning of the mouse obese gene and its human homologue.Nature,1994,372:425 被引量:1
  • 2Tartaglia LA,Dembski M,Weng X,et al.Identificanition and expression cloning of a leptin receptor.Cell,1995,83:1263 被引量:1
  • 3Lee GH,Proenca R,Montez JM,et al.Abnormal splicing of the leptin receptor in diabetic mice.Nature,1996,379:622 被引量:1
  • 4Sinha MK,Opentanova I,Ohannesian JP,et al.Evidence of free and bound leptin in human circulation.Studies in lean and obese subjects and during ahort-term fasting.J Clin Invest,1996,98:1277 被引量:1
  • 5Lollmann B,Gruninger S,Stricker-Krongrad A,et al.Detection and quantification of the leptin receptor splice variants Ob-Ra,b and e in different mouse tissues.Bioche Biophy Res Com,1997,238:648 被引量:1
  • 6Wang MY,Zhou YT,Christopher B,et al.A novel leptin receptor isoform in rat.FEBS,1996,392:87 被引量:1
  • 7Eckert Ed,Pomeroy C,Raymond N,et al.Leptin in anorexiz nervose.J Clin Endo Meta,1998,83:791 被引量:1
  • 8Moller N,O'Brien P,Nair KS,et al.Disruption of the reationship between fat content and leptin levels with aging in humans.J Clin Endocrinol Meta,1998,83:931 被引量:1
  • 9Blum WF,Englaro P,Hanitsch S,et al.Plasma leptin levels in healthy children and adolescents:dependence on boby mass index,body fat mass,gender,pubertal stage,and testosterone.J Clin Endocrinol Metab,1997,82(9):2904 被引量:1
  • 10Park HY,Kwon HM,Lim HJ,et al.Potential role of leptin in angiogenesis:leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro.Exp Mol Med,2001,33(2):95 被引量:1

共引文献14

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部