期刊文献+

BCL-2家族蛋白对线粒体膜通透作用的调控和caspases的影响 被引量:7

下载PDF
导出
摘要 线粒体通过释放凋亡蛋白来激活caspases和其它的细胞死亡受体,从而在转运细胞死亡信号中发挥重要作用。BCL-2家族蛋白位于线粒体膜上,对于凋亡因子来说,它具有调节线粒体膜通透性(MM P)的功能。最近的一些研究结果表明,BCL-2家族蛋白可能在释放线粒体凋亡因子中具有重要作用。
作者 王静 崔玉东
出处 《中国畜牧兽医》 CAS 2006年第4期28-30,共3页 China Animal Husbandry & Veterinary Medicine
  • 相关文献

参考文献23

  • 1Adrain C,Creagh E M,Martin S J.Apoptosis-associated release of SMAC/DIABLO from mitochondria requires caspases and is blocked by Bcl-2.EMBO J,2001,20:6627~6636. 被引量:1
  • 2Arnoult D,Gaume B,Karbowski M,et al.Mitochondrial release of AIF and EndoG requires caspases activation downsrream of BAX/Bak-mediated permeabilization.EmBO J,2003,22:4385~4399. 被引量:1
  • 3Bergeron L,Perez G I,Macdonald G,et al.Defect in regulation of apoptosis in caspases-2-deficient mice.Genes Dev,1998,12:1304~1314. 被引量:1
  • 4Bossy-Wetzel E,Newmeyer D D,Green D R.Mitochondrial cytochrome c release in apoptosis occurs upstream of mitochondrial transmembrane depolarization.EMBO J,1998,17:37~49. 被引量:1
  • 5Cheng E H,Sheiko T V,Fisher J K,et al.VDAC2 inhibits BAK activation and mitochondrial apoptosis.Science,2003,301:513~517. 被引量:1
  • 6Goldstein J C,Waterhouse N J,Juin P,et al.The coordinate release of cytochrome c during apoptosis is rapid,complete and kinetically invariate.Nat Cell Bio,2000,2:156~162. 被引量:1
  • 7Gou Y,Srinivasula S M,Druilhe A,et al.Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria.J Bio Chem,2002,277:13430~13437. 被引量:1
  • 8Gross A,Yin X M,Wang K,et al.Caspase cleaved BID targets mitochondria and is required for not tumor necrosis factor-R1/Fas death.J Bio Chem,1999,274:1156~1163. 被引量:1
  • 9Guo B,Zhai D,Cabezas E,et al.Humanin peptide suppresses apoptosis by interfering with BAX activation.Nature,2003,423:456~461. 被引量:1
  • 10Jiang X,Wang X.Cytochrome-c-mediated apoptosis.Annu Rev Biochem,2004,73:87~106. 被引量:1

同被引文献53

  • 1苗明三,孙艳红.玉米须总皂苷降糖作用研究[J].中国中药杂志,2004,29(7):711-712. 被引量:77
  • 2钟金城,赵素君,陈智华,马志杰.牦牛品种的遗传多样性及其分类研究[J].中国农业科学,2006,39(2):389-397. 被引量:79
  • 3Eguchi Y, Ewert D , Tsujimoto Y. Isolation and characterization of the chicken bcl-2 gene .. expression in a variety of tissues including lymphoid and neuronal organs in adult and embryo [J]. Nucleic Acids Res, 1992,20(16):4187-4192. 被引量:1
  • 4Ines K, Renate W, Peter P, et al. Analysis of a regulatory element in the 5'-untranslated region of the bcl-2 gene[J]. FEBS Letters, 1997,406 : 31-32. 被引量:1
  • 5Jimenez G S ,Khan S H ,Stommel J M ,et al. P53 regulation by post- translational modification and nuclear retention in response to diverse stresses[J]. Oneogene, 1999,18 : 76561. 被引量:1
  • 6Korsmeyer S J . BCl-2 initiate a new category of oncogenes : r egulators of cell death. Blood,1992,80(4) :879-886. 被引量:1
  • 7Maja T, Markus C, Bernd K. Cloning and functional analysis of cDNA encoding the hamster bcl22 protein [J].Biochemical and Biophysical Research Communications, 2000,275 : 899 - 903. 被引量:1
  • 8Zamzami N, Brenner G, Marzo I. Permeability transition proe inapoptosis[J]. Biosci Rep, 1997,17 : 67. 被引量:1
  • 9Zhang L, Miler RG, Zhang J. Characterization of apoptosis-resistant antigen-specific T cells in vivo[J]. Exp Med,1996,183(5):2065-2073. 被引量:1
  • 10Hara T. Omura-Minamisawa M, Chao C, et al. Bcl-2 inhibitors potentiate the cytotoxic effects of radiation in Bcl-2 overexpressing radioresistant tumor cells[J]. Int J Radiat Oncol Biol Phys,2005,61(2):517-528. 被引量:1

引证文献7

二级引证文献24

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部