摘要
目的:探讨丙泊酚在ICU机械通气患者镇静治疗中的效果及作用。方法:全组共30例,机械通气后采用丙泊酚镇静治疗,观察镇静效果达R am say氏分级III^IV级时间、动态监测给药前、后和停药时呼吸、循环参数的变化,并与治疗前进行比较。结果:丙泊酚镇静治疗后起效快,用药后血压、心率逐渐稳定;呼吸频率、血氧饱和度、氧和指数亦有明显改善(P<0.05)。结论:丙泊酚能达到ICU机械通气患者所需的镇静要求,根据临床需要调整镇静时间和深度。
Objective To discuss the effect of propofol on mechanical ventilation patients in intensive care unit. Methods A clinical retrospective analysis was carried out to investigate 30 patients, who required mechanical ventilation and sedated by propofol. The time to get Ramsay sedation level Ⅲ-Ⅳ was observed. To compare parameters of pneusis and circulation before and after giving porofol. Results The sedative time of propofol was short. The patients＇ blood pressure, heart rate, respirotary, SpO2, PaO2, PaO2/FiO2 were better than before （P〈0.05）. Conclusion Propofol has a remarkable effect on the mechanical ventilation patients in intensive care unit. The sedative time and sedation level may be adjusted through clinical observation.
出处
《实用诊断与治疗杂志》
2006年第5期326-327,共2页
Journal of Practical Diagnosis and Therapy
关键词
丙泊酚
ICU
机械通气
治疗
Propofol
intensive care unit
mechanical ventilations therapy
