摘要
本文检测170例伤寒患者血清腺苷脱氨酶(ADA),活性(U·L-1)为100.85±36.01;149例健康人为20.00±5.10;227例非伤寒发热患者为36.44±14.54~50.65±1.91。结果比较:伤寒组明显高于非伤寒组,非伤寒发热组明显高于健康组。以≥70为阳性,伤寒组阳性率为80.6%(137/170),健康组为0%,非伤寒组为7.9%(18/227),组间有非常显著性差异。ADA检测对伤寒诊断敏感性为92.1%,诊断正确率为87%。表明ADA检测对伤寒早期诊断和鉴别诊断有重要临床价值。
The adenosine deaminase ( ADA) activity in serum was determined from 170 patients with typhoid(Group I),227 non-typhoid patients with fever(Group I)and 149 healthy persons(GroupⅢ).The results were 100, 85±36.0u/L,36.44±14.54~50.65± 1.91/L and 20.0±5.1u/L(X±S)respectively. The differences among the three groups were statistically significant. The positive rate is 80.6%for Group I.7.9%for(Group I,and 0%for Group Ⅲ. If ADA≥70 u/L in serum is regarded as the positive level for typhoid. The speciflcity for typhoid diagnosis is 92.1%and the diagnostic correct rate 87%. The study showed that ADA determination in serum was of important value in the early and differential diagnosis for typhoid.