摘要
目的通过长期随访观察冠心病患者再灌注前后多巴酚丁胺负荷超声心动图的改变,探讨在不同负荷条件下再灌注存活心肌的变化。方法行经皮冠状动脉成形术加支架术的冠心病患者52例,于术前、术后6个月及3年应用多巴酚丁胺负荷超声心动图观察其不同负荷条件下左室射血分数(LVEF)和室壁运动的变化。结果术后6个月静息状态LVEF提高≥5%患者分为A组,其余归为B组。A组和B组患者的基本情况无明显差别。A组患者术后6个月及术后3年静息及不同负荷条件下LVEF持续增加,左室室壁运动记分指数(WMSI)持续减低。B组患者静息LVEF提高不明显,但术后6个月、3年在负荷条件下LVEF持续升高,WMSI持续减低。结论负荷条件下LVEF和WMSI的改变对评价患者存活心肌再灌注具有重要价值。
Objective To evaluate the response of left ventricular ejection fraction （LVEF） to different doses dobutamine infusion in coronary artery disease patients, and detetect the changes of viable myocardium afte revascularization. Methods Before and 6 months, 3 years after percutaneous transluminal coronary angioplasty（PTCA） or PTCA plus stent, 52 patients with ischaemic cardiomyopathy underwent dobutamine stress echocardiography. The response of LVEF and wall motion during dobutamine stress echocardiography were compared in the patients. Results All the patients were divided into two groups, group A with,and group B without significant improvement in resting LVEF（≥5 %）. Group A and B were comparable in baseline characteristics and resting LVEF. After revascularization, the LVEF response during dobutamine stress echocardiography improved significantly and left ventricular wall mation score index （WMSI） decreased significantly in group A. In group B resting LVEF did not improve significantly after revascularization,but stress LVEF improved significantly and left ventricular WMSI decreased significantly in 6 months and 3 years. Conclusions To assessment the benefit of revascularization in patients with viable myocardium stress LVEF and WMSI are good compensation.
出处
《中华超声影像学杂志》
CSCD
2006年第4期270-272,共3页
Chinese Journal of Ultrasonography
